Phylogeny of betanodaviruses and molecular evolution of their RNA polymerase and coat proteins

• Published in: Molecular phylogenetics and evolution Vol. 43; no. 1; pp. 298 - 308
• Main Authors: Toffolo, Vania, Negrisolo, Enrico, Maltese, Chiara, Bovo, Giuseppe, Belvedere, Paola, Colombo, Lorenzo, Valle, Luisa Dalla
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.04.2007
• Subjects: Base Sequence; Betanodavirus; Capsid Proteins - genetics; DNA Primers; DNA-Directed RNA Polymerases - genetics; Evolution, Molecular; Fish nodavirdae; Likelihood Functions; Models, Genetic; Molecular evolution; Molecular Sequence Data; Nodaviridae - enzymology; Nodaviridae - genetics; Phylogeny; Reverse Transcriptase Polymerase Chain Reaction; RNA1 and RNA2; Selection, Genetic; Sequence Alignment; Sequence Analysis, DNA; Molecular evolution; RNA1 and RNA2; Phylogeny; Fish nodavirdae

The betanodaviruses are the causative agent of the disease viral nervous necrosis in fishes. Betanodavirus genome consists of two single-stranded positive-sense RNA molecules (RNA1 and RNA2). RNA1 gene encodes the RNA polymerase, named also protein A, while RNA2 encodes the coat protein precursor, t...