A multiple-network poroelastic model for biological systems and application to subject-specific modelling of cerebral fluid transport

• Published in: International journal of engineering science Vol. 147; p. 103204
• Main Authors: Guo, Liwei, Vardakis, John C., Chou, Dean, Ventikos, Yiannis
• Format: Journal Article
• Language: English
• Published: Oxford Elsevier Ltd 01.02.2020; Elsevier BV
• Subjects: Biological models (mathematics); Blood; Body fluids; Boundary conditions; Brain; Computational fluid dynamics; Exact solutions; Finite element method; Formability; Multiple fluids; Numerical analysis; Numerical models; Poroelasticity; Porous media; Smoking; Subject-specific modelling; Three dimensional models; Tissues; Transport phenomena; Transport phenomenon; Finite element method; Brain; Transport phenomenon; Subject-specific modelling; Multiple fluids; Poroelasticity

Biological tissue can be viewed as porous, permeable and deformable media infiltrated by fluids, such as blood and interstitial fluid. A finite element model has been developed based on the multiple-network poroelastic theory to investigate transport phenomenon in such biological systems. The govern...