Prasugrel Compared With High Loading- and Maintenance-Dose Clopidogrel in Patients With Planned Percutaneous Coronary Intervention: The Prasugrel in Comparison to Clopidogrel for Inhibition of Platelet Activation and Aggregation–Thrombolysis in Myocardial Infarction 44 Trial - Wiviott, Stephen D.; Trenk, Dietmar; Frelinger, Andrew L.; O’Donoghue, Michelle; Neumann, Franz-Josef; Michelson, Alan D.; Angiolillo, Dominick J.; Hod, Hanoch; Montalescot, Gilles; Miller, Debra L.; Jakubowski, Joseph A.; Cairns, Richard; et al. (Circulation (New York, N.Y.), 2007)
Keywords: Aged; Angioplasty, Balloon, Coronary; Biological and medical sciences; Blood and lymphatic vessels; Blood coagulation. Blood cells; Cardiology. Vascular system; Combined Modality Therapy; Coronary heart disease; Cross-Over Studies; Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous; Female; Fundamental and applied biological sciences. Psychology; Heart; Humans; Male; Medical sciences; Middle Aged; Molecular and cellular biology; Myocardial Infarction - drug therapy; Piperazines - administration & dosage; Piperazines - pharmacokinetics; Platelet; Platelet Activation - drug effects; Platelet Aggregation Inhibitors - administration & dosage; Platelet Aggregation Inhibitors - pharmacokinetics; Prasugrel Hydrochloride; Thiophenes - administration & dosage; Thiophenes - pharmacokinetics; Thrombolytic Therapy - methods; Ticlopidine - administration & dosage; Ticlopidine - analogs & derivatives; Ticlopidine - pharmacokinetics; Treatment Outcome; Human; Myocardial infarction; antiplatelet agents; Cardiovascular disease; Anticoagulant; Coronary heart disease; Thrombosis; Antiplatelet agent; platelets; Percutaneous route; Vascular disease; Aggregation; Prasugrel; coronary disease; Platelet; anticoagulants; Clopidogrel; Thienopyridine derivative; High dose; Comparative study