Sildenafil Prevents Endothelial Dysfunction Induced by Ischemia and Reperfusion via Opening of Adenosine Triphosphate–Sensitive Potassium Channels: A Human In Vivo Study - Gori, Tommaso; Sicuro, Silvia; Dragoni, Saverio; Donati, Giovanni; Forconi, Sandro; Parker, John D. (Circulation (New York, N.Y.), 2005)
Keywords: Adult; Biological and medical sciences; Blood and lymphatic vessels; Cardiology. Vascular system; Cardiovascular system; Cross-Over Studies; Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous; Double-Blind Method; Drug toxicity and drugs side effects treatment; Endothelium, Vascular - drug effects; Endothelium, Vascular - physiopathology; Glyburide - pharmacology; Humans; Male; Medical sciences; Middle Aged; Myocardial Ischemia - drug therapy; Myocardial Ischemia - metabolism; Myocardial Ischemia - physiopathology; Myocardial Reperfusion Injury - prevention & control; Pharmacology. Drug treatments; Piperazines - administration & dosage; Piperazines - pharmacology; Placebo Effect; Potassium Channels - metabolism; Purines; Sildenafil Citrate; Sulfones; Toxicity: blood; Vasodilator agents. Cerebral vasodilators; Human; endothelium; Purine nucleoside; Adenosine; Vasodilator agent; 3',5'-Cyclic-GMP phosphodiesterase; Enzyme; Enzyme inhibitor; Cardiovascular disease; Esterases; Triphosphates; Phosphoric diester hydrolases; Antiarrhythmic agent; Inorganic element; Ischemia; Hydrolases; Sildenafil; Potassium; reperfusion