Analytical approaches to poly-γ-glutamate: Quantification, molecular size determination, and stereochemistry investigation

Poly-γ-glutamate, a nylon-like polyamide material typically consisting of both enantiomers of glutamate, exhibits reasonable biodegradability and its multi-functionality is attracting particular attention. Thus, its industrial application as a versatile and chiral polymer is in increasing demands. P...

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Published inJournal of chromatography. B, Analytical technologies in the biomedical and life sciences Vol. 879; no. 29; pp. 3096 - 3101
Main Author Ashiuchi, Makoto
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 01.11.2011
Subjects
bacteria
biocatalysts
biodegradability
chromatography
enantiomers
glutamic acid
industrial applications
Molecular size
Molecular Weight
Poly-γ-glutamate
polyamides
Polyglutamic Acid - analogs & derivatives
Polyglutamic Acid - analysis
Polyglutamic Acid - chemistry
Quantification
Stereochemistry
Stereoisomerism
Molecular size
Stereochemistry
Quantification
Poly-γ-glutamate
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Summary:Poly-γ-glutamate, a nylon-like polyamide material typically consisting of both enantiomers of glutamate, exhibits reasonable biodegradability and its multi-functionality is attracting particular attention. Thus, its industrial application as a versatile and chiral polymer is in increasing demands. Poly-γ-glutamate is presently synthesized using several biocatalysts ( e.g., bacterial cells), but the uncontrollable structural diversity of such biosynthesized materials is an area of concern. This review highlights analytical approaches of interest to assure the functional and structural reproducibility of poly-γ-glutamate.
Bibliography:http://dx.doi.org/10.1016/j.jchromb.2011.03.029
ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:1570-0232
1873-376X
DOI:10.1016/j.jchromb.2011.03.029