A Role for Prior Knowledge in Statistical Classification of the Transition from Mild Cognitive Impairment to Alzheimer's Disease

• Published in: Journal of Alzheimer's disease Vol. 83; no. 4; p. 1859
• Main Authors: Liu, Zihuan, Maiti, Tapabrata, Bender, Andrew R
• Format: Journal Article
• Language: English
• Published: Netherlands 01.01.2021
• Subjects: Aged; Alzheimer Disease - classification; Brain - pathology; Cognitive Dysfunction - classification; Female; Humans; Machine Learning; Magnetic Resonance Imaging; Male; Support Vector Machine; mild cognitive impairment; support vector machine; variable selection; Alzheimer’s disease; classification; machine learning

The transition from mild cognitive impairment (MCI) to dementia is of great interest to clinical research on Alzheimer's disease and related dementias. This phenomenon also serves as a valuable data source for quantitative methodological researchers developing new approaches for classification....