Tissue iron distribution in patients with anemia of inflammation: Results of a pilot study

• Published in: American journal of hematology Vol. 98; no. 6; pp. 890 - 899
• Main Authors: Lanser, Lukas, Plaikner, Michaela, Schroll, Andrea, Burkert, Francesco Robert, Seiwald, Stefanie, Fauser, Josia, Petzer, Verena, Bellmann‐Weiler, Rosa, Fritsche, Gernot, Tancevski, Ivan, Duftner, Christina, Pircher, Andreas, Seeber, Andreas, Zoller, Heinz, Kremser, Christian, Henninger, Benjamin, Weiss, Günter
• Format: Journal Article
• Language: English
• Published: Hoboken, USA John Wiley & Sons, Inc 01.06.2023; Wiley Subscription Services, Inc
• Subjects: Anemia; Anemia - etiology; Anemia, Iron-Deficiency - complications; Animal models; Animals; Ferritin; Ferritins; Hematology; Hepcidin; Hepcidins; Inflammation; Inflammatory diseases; Interleukin 6; Iron; Iron - metabolism; Iron Deficiencies; Iron deficiency; Macrophages; Magnetic resonance imaging; Nutrient deficiency; Pancreas; Pilot Projects; Prospective Studies; Spleen

Anemia of inflammation (AI) is frequently present in subjects with inflammatory disorders, primarily caused by inflammation‐driven iron retention in macrophages. So far, only limited data on qualitative and quantitative estimates of tissue iron retention in AI patients exist. We performed a prospect...