Long noncoding RNA LINC00460 promotes carcinogenesis via sponging miR‐613 in papillary thyroid carcinoma

• Published in: Journal of cellular physiology Vol. 234; no. 7; pp. 11431 - 11439
• Main Authors: Feng, Li, Yang, Bin, Tang, Xiao‐Di
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.07.2019
• Subjects: Carcinogenesis; Carcinogens; Carcinoma, Papillary - metabolism; Cell Line, Tumor; Cell migration; Cell Movement; Cell Proliferation; Gene expression; Gene Expression Regulation, Neoplastic - physiology; Gene Knockdown Techniques; Humans; Invasiveness; Kinases; lncRNA LINC00460; Lymph nodes; Metastases; Metastasis; MicroRNAs - genetics; MicroRNAs - metabolism; miR‐613; Papillary thyroid carcinoma; Phosphotransferases (Alcohol Group Acceptor) - genetics; Phosphotransferases (Alcohol Group Acceptor) - metabolism; Ribonucleic acid; RNA; RNA, Long Noncoding - genetics; RNA, Long Noncoding - metabolism; RNA, Untranslated - genetics; RNA, Untranslated - metabolism; Sphingosine kinase; SphK2; Thyroid; Thyroid cancer; Thyroid Gland; Thyroid Neoplasms - metabolism; Up-Regulation; lncRNA LINC00460; SphK2; papillary thyroid carcinoma; miR-613

Long intergenic noncoding RNA 460 (LINC00460) has been identified as a critical regulator for multiple types of cancers. However, the biological role and underlying mechanism in human papillary thyroid carcinoma (PTC) still remain unclear and need to be uncovered. This study was aimed to ascertain t...