Pediatric living donor liver transplantation with large‐for‐size left lateral segment grafts

Usage of “large‐for‐size” left lateral segment (LLS) liver grafts in children with high graft to recipient weight ratio (GRWR) is controversial due to concerns about increased recipient complications. During the study period, 77 pediatric living donor liver transplantations (LDLTs) with LLS grafts w...

Full description

Saved in:
Bibliographic Details
Published inAmerican journal of transplantation Vol. 20; no. 2; pp. 504 - 512
Main Authors Goldaracena, Nicolas, Echeverri, Juan, Kehar, Mohit, DeAngelis, Maria, Jones, Nicola, Ling, Simon, Kamath, Binita M., Avitzur, Yaron, Ng, Vicky L., Cattral, Mark S., Grant, David R., Ghanekar, Anand
Format Journal Article
LanguageEnglish
Published United States Elsevier Limited 01.02.2020
Subjects
Online AccessGet full text

Cover

Loading…
Abstract Usage of “large‐for‐size” left lateral segment (LLS) liver grafts in children with high graft to recipient weight ratio (GRWR) is controversial due to concerns about increased recipient complications. During the study period, 77 pediatric living donor liver transplantations (LDLTs) with LLS grafts were performed. We compared recipients with GRWR ≥2.5% (GR‐High = 50) vs GRWR <2.5% (GR‐Low = 27). Median age was higher in the GR‐Low group (40 vs 8 months, P> .0001). Graft (GR‐High: 98%, 98%, 98% vs GR‐Low: 96%, 93%, 93%) and patient (GR‐High: 98%, 98%, 98% vs GR‐Low: 100%, 96%, 96%) survival at 1, 3, and 5 years was similar between groups (P = NS). Overall complications were also similar (34% vs 30%; P = .8). Hepatic artery and portal vein thrombosis following transplantation was not different (P = NS). Delayed abdominal fascia closure was more common in GR‐High patients (17 vs 1; P = .002). Subgroup analysis comparing recipients with GRWR ≥4% (GR‐XL = 20) to GRWR <2.5% (GRWR‐Low = 27) revealed that delayed abdominal fascia closure was more common in the GR‐XL group, but postoperative complications and graft and patient survival were similar. We conclude that pediatric LDLT with large‐for‐size LLS grafts is associated with excellent clinical outcomes. There is an increased need for delayed abdominal closure with no compromise of long‐term outcomes. The use of high GRWR expands the donor pool and improves timely access to the benefits of transplantation without extra risks. The use of large‐for‐size left lateral segment grafts in pediatric living donor liver transplantation with potential delayed abdominal wall closure offers a safe and effective option to mitigate organ shortage.
AbstractList Usage of "large-for-size" left lateral segment (LLS) liver grafts in children with high graft to recipient weight ratio (GRWR) is controversial due to concerns about increased recipient complications. During the study period, 77 pediatric living donor liver transplantations (LDLTs) with LLS grafts were performed. We compared recipients with GRWR ≥2.5% (GR-High = 50) vs GRWR <2.5% (GR-Low = 27). Median age was higher in the GR-Low group (40 vs 8 months, P> .0001). Graft (GR-High: 98%, 98%, 98% vs GR-Low: 96%, 93%, 93%) and patient (GR-High: 98%, 98%, 98% vs GR-Low: 100%, 96%, 96%) survival at 1, 3, and 5 years was similar between groups (P = NS). Overall complications were also similar (34% vs 30%; P = .8). Hepatic artery and portal vein thrombosis following transplantation was not different (P = NS). Delayed abdominal fascia closure was more common in GR-High patients (17 vs 1; P = .002). Subgroup analysis comparing recipients with GRWR ≥4% (GR-XL = 20) to GRWR <2.5% (GRWR-Low = 27) revealed that delayed abdominal fascia closure was more common in the GR-XL group, but postoperative complications and graft and patient survival were similar. We conclude that pediatric LDLT with large-for-size LLS grafts is associated with excellent clinical outcomes. There is an increased need for delayed abdominal closure with no compromise of long-term outcomes. The use of high GRWR expands the donor pool and improves timely access to the benefits of transplantation without extra risks.
Usage of “large‐for‐size” left lateral segment (LLS) liver grafts in children with high graft to recipient weight ratio (GRWR) is controversial due to concerns about increased recipient complications. During the study period, 77 pediatric living donor liver transplantations (LDLTs) with LLS grafts were performed. We compared recipients with GRWR ≥2.5% (GR‐High = 50) vs GRWR <2.5% (GR‐Low = 27). Median age was higher in the GR‐Low group (40 vs 8 months, P> .0001). Graft (GR‐High: 98%, 98%, 98% vs GR‐Low: 96%, 93%, 93%) and patient (GR‐High: 98%, 98%, 98% vs GR‐Low: 100%, 96%, 96%) survival at 1, 3, and 5 years was similar between groups (P = NS). Overall complications were also similar (34% vs 30%; P = .8). Hepatic artery and portal vein thrombosis following transplantation was not different (P = NS). Delayed abdominal fascia closure was more common in GR‐High patients (17 vs 1; P = .002). Subgroup analysis comparing recipients with GRWR ≥4% (GR‐XL = 20) to GRWR <2.5% (GRWR‐Low = 27) revealed that delayed abdominal fascia closure was more common in the GR‐XL group, but postoperative complications and graft and patient survival were similar. We conclude that pediatric LDLT with large‐for‐size LLS grafts is associated with excellent clinical outcomes. There is an increased need for delayed abdominal closure with no compromise of long‐term outcomes. The use of high GRWR expands the donor pool and improves timely access to the benefits of transplantation without extra risks. The use of large‐for‐size left lateral segment grafts in pediatric living donor liver transplantation with potential delayed abdominal wall closure offers a safe and effective option to mitigate organ shortage.
Usage of “large‐for‐size” left lateral segment (LLS) liver grafts in children with high graft to recipient weight ratio (GRWR) is controversial due to concerns about increased recipient complications. During the study period, 77 pediatric living donor liver transplantations (LDLTs) with LLS grafts were performed. We compared recipients with GRWR ≥2.5% (GR‐High = 50) vs GRWR <2.5% (GR‐Low = 27). Median age was higher in the GR‐Low group (40 vs 8 months, P> .0001). Graft (GR‐High: 98%, 98%, 98% vs GR‐Low: 96%, 93%, 93%) and patient (GR‐High: 98%, 98%, 98% vs GR‐Low: 100%, 96%, 96%) survival at 1, 3, and 5 years was similar between groups (P = NS). Overall complications were also similar (34% vs 30%; P = .8). Hepatic artery and portal vein thrombosis following transplantation was not different (P = NS). Delayed abdominal fascia closure was more common in GR‐High patients (17 vs 1; P = .002). Subgroup analysis comparing recipients with GRWR ≥4% (GR‐XL = 20) to GRWR <2.5% (GRWR‐Low = 27) revealed that delayed abdominal fascia closure was more common in the GR‐XL group, but postoperative complications and graft and patient survival were similar. We conclude that pediatric LDLT with large‐for‐size LLS grafts is associated with excellent clinical outcomes. There is an increased need for delayed abdominal closure with no compromise of long‐term outcomes. The use of high GRWR expands the donor pool and improves timely access to the benefits of transplantation without extra risks.
Author Kehar, Mohit
Ng, Vicky L.
DeAngelis, Maria
Ghanekar, Anand
Goldaracena, Nicolas
Cattral, Mark S.
Jones, Nicola
Ling, Simon
Grant, David R.
Echeverri, Juan
Avitzur, Yaron
Kamath, Binita M.
Author_xml – sequence: 1
  givenname: Nicolas
  orcidid: 0000-0002-6623-5561
  surname: Goldaracena
  fullname: Goldaracena, Nicolas
  organization: University of Virginia
– sequence: 2
  givenname: Juan
  surname: Echeverri
  fullname: Echeverri, Juan
  organization: University Health Network
– sequence: 3
  givenname: Mohit
  surname: Kehar
  fullname: Kehar, Mohit
  organization: Hospital for Sick Children
– sequence: 4
  givenname: Maria
  surname: DeAngelis
  fullname: DeAngelis, Maria
  organization: Hospital for Sick Children
– sequence: 5
  givenname: Nicola
  surname: Jones
  fullname: Jones, Nicola
  organization: Hospital for Sick Children
– sequence: 6
  givenname: Simon
  surname: Ling
  fullname: Ling, Simon
  organization: Hospital for Sick Children
– sequence: 7
  givenname: Binita M.
  surname: Kamath
  fullname: Kamath, Binita M.
  organization: Hospital for Sick Children
– sequence: 8
  givenname: Yaron
  surname: Avitzur
  fullname: Avitzur, Yaron
  organization: Hospital for Sick Children
– sequence: 9
  givenname: Vicky L.
  surname: Ng
  fullname: Ng, Vicky L.
  organization: Hospital for Sick Children
– sequence: 10
  givenname: Mark S.
  surname: Cattral
  fullname: Cattral, Mark S.
  organization: Hospital for Sick Children
– sequence: 11
  givenname: David R.
  surname: Grant
  fullname: Grant, David R.
  organization: Hospital for Sick Children
– sequence: 12
  givenname: Anand
  surname: Ghanekar
  fullname: Ghanekar, Anand
  email: anand.ghanekar@uhn.ca
  organization: Hospital for Sick Children
BackLink https://www.ncbi.nlm.nih.gov/pubmed/31550068$$D View this record in MEDLINE/PubMed
BookMark eNp1kMtOAyEUhonReKkufAEziRtdVIGZYWBpGq9poou6RjpzqDRTqEBt6spH8Bl9EqmtLkxkwS1fvvPn30Ob1llA6JDgM5LWuRrHM1IyLDbQLmEYdxkp8s3fe17uoL0QxhiTinK6jXZyUpYYM76Lnh6gMSp6U2eteTV2lDXOOr98gM-iVzZMW2WjisbZbG7ic9YqP4LP9w_tfNqDeYOsBR3TfwSv2izAaAI2ZiOvdAz7aEurNsDB-uygx6vLQe-m27-_vu1d9Lt1zrnoAiNac6ZpQViNARrOqorxYV1WRBWCpMSFoLWmWAwFLjUFygVWuGrosoIi76CTlXfq3csMQpQTE2poU3hwsyApFYyxkhOS0OM_6NjNvE3pJM2LQlSi5Evh6YqqvQvBg5ZTbybKLyTBcjlTptrld-2JPVobZ8MJNL_kT88JOF8Bc9PC4n-TvLgbrJRfzGCPBg
CitedBy_id crossref_primary_10_1016_j_jpedsurg_2022_02_034
crossref_primary_10_12677_ACM_2024_141073
crossref_primary_10_1016_j_jss_2022_12_022
crossref_primary_10_1111_pan_14562
crossref_primary_10_1097_TP_0000000000004730
crossref_primary_10_52604_alt_22_0022
crossref_primary_10_3389_ti_2022_10437
crossref_primary_10_1016_j_jceh_2024_101349
crossref_primary_10_1097_TXD_0000000000001551
crossref_primary_10_1111_petr_14159
crossref_primary_10_1111_petr_14543
crossref_primary_10_3390_children8070579
crossref_primary_10_1016_j_hpb_2021_09_024
crossref_primary_10_1111_petr_13683
crossref_primary_10_1111_petr_14298
crossref_primary_10_6002_ect_2020_0308
crossref_primary_10_1111_petr_14044
crossref_primary_10_1111_petr_14132
crossref_primary_10_1111_petr_14518
crossref_primary_10_1016_j_iliver_2022_08_003
crossref_primary_10_1111_petr_14405
crossref_primary_10_3389_fped_2023_1242009
crossref_primary_10_1055_s_0044_1782668
Cites_doi 10.1016/j.jamcollsurg.2017.12.042
10.1111/ajt.14489
10.1111/j.1399-3046.2004.00264.x
10.1111/j.1600-6143.2004.00398.x
10.1111/ajt.14875
10.1002/lt.24048
10.1097/MOT.0000000000000280
10.1097/00007890-199901270-00024
10.1111/petr.12985
10.1111/petr.12592
10.1097/TXD.0000000000000865
10.1097/TP.0b013e31827a93b4
10.1007/s00423-012-1020-y
10.1053/j.sempedsurg.2017.07.014
10.1097/SLA.0000000000001337
10.1097/TP.0000000000001442
10.1097/01.tp.0000263340.82489.18
10.1016/j.transproceed.2010.02.059
10.1097/TP.0b013e3181c5cdc1
10.1097/TP.0000000000002249
10.1111/ajt.15041
10.1053/j.sempedsurg.2017.07.008
10.1111/ajt.15085
10.1002/lt.21027
10.1111/j.1600-6143.2010.03274.x
ContentType Journal Article
Copyright 2019 The American Society of Transplantation and the American Society of Transplant Surgeons
2019 The American Society of Transplantation and the American Society of Transplant Surgeons.
2020 The American Society of Transplantation and the American Society of Transplant Surgeons
Copyright_xml – notice: 2019 The American Society of Transplantation and the American Society of Transplant Surgeons
– notice: 2019 The American Society of Transplantation and the American Society of Transplant Surgeons.
– notice: 2020 The American Society of Transplantation and the American Society of Transplant Surgeons
DBID CGR
CUY
CVF
ECM
EIF
NPM
AAYXX
CITATION
7QP
7T5
7U9
H94
K9.
7X8
DOI 10.1111/ajt.15609
DatabaseName Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
CrossRef
Calcium & Calcified Tissue Abstracts
Immunology Abstracts
Virology and AIDS Abstracts
AIDS and Cancer Research Abstracts
ProQuest Health & Medical Complete (Alumni)
MEDLINE - Academic
DatabaseTitle MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
CrossRef
AIDS and Cancer Research Abstracts
ProQuest Health & Medical Complete (Alumni)
Immunology Abstracts
Virology and AIDS Abstracts
Calcium & Calcified Tissue Abstracts
MEDLINE - Academic
DatabaseTitleList MEDLINE

AIDS and Cancer Research Abstracts
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
DeliveryMethod fulltext_linktorsrc
EISSN 1600-6143
EndPage 512
ExternalDocumentID 10_1111_ajt_15609
31550068
AJT15609
Genre article
Journal Article
GroupedDBID ---
.3N
.GA
.Y3
05W
0SF
10A
1OC
23M
24P
2WC
31~
33P
36B
3SF
4.4
50Y
50Z
51W
51X
52M
52N
52O
52P
52R
52S
52T
52U
52V
52W
52X
53G
5GY
5HH
5LA
5VS
66C
6J9
702
7PT
8-0
8-1
8-3
8-4
8-5
8UM
930
A01
A03
AAESR
AAEVG
AAHHS
AALRI
AAONW
AASGY
AAXRX
AAXUO
AAZKR
ABCQN
ABCUV
ABEML
ABJNI
ABPPZ
ABPVW
ABXGK
ACAHQ
ACCFJ
ACCZN
ACGFO
ACGFS
ACMXC
ACPOU
ACPRK
ACSCC
ACXBN
ACXQS
ADBBV
ADEOM
ADIZJ
ADKYN
ADMGS
ADOZA
ADVLN
ADXAS
ADZMN
ADZOD
AEEZP
AEGXH
AEIMD
AENEX
AEQDE
AEUQT
AFBPY
AFEBI
AFGKR
AFPWT
AFZJQ
AHMBA
AIACR
AIAGR
AITUG
AIURR
AIWBW
AJAOE
AJBDE
AKRWK
ALAGY
ALMA_UNASSIGNED_HOLDINGS
ALUQN
AMBMR
AMRAJ
AMYDB
ATUGU
AZBYB
AZVAB
BAFTC
BAWUL
BHBCM
BMXJE
BROTX
BRXPI
BY8
C45
CAG
COF
CS3
D-6
D-7
D-E
D-F
DCZOG
DIK
DPXWK
DR2
DRFUL
DRMAN
DRSTM
E3Z
EBS
EJD
ESX
EX3
F00
F01
F04
F5P
FDB
FIJ
FUBAC
G-S
G.N
GODZA
GX1
H.X
HF~
HZI
HZ~
IHE
IPNFZ
IX1
J0M
K48
KBYEO
LATKE
LC2
LC3
LEEKS
LH4
LITHE
LOXES
LP6
LP7
LUTES
LW6
LYRES
M41
MK4
MRFUL
MRMAN
MRSTM
MSFUL
MSMAN
MSSTM
MXFUL
MXMAN
MXSTM
N04
N05
N9A
NF~
O66
O9-
OIG
OK1
OVD
P2P
P2W
P2X
P2Z
P4B
P4D
PQQKQ
Q.N
Q11
QB0
R.K
ROL
RX1
SUPJJ
TEORI
TR2
UB1
V8K
W8V
W99
WBKPD
WHWMO
WIH
WIJ
WIK
WIN
WOHZO
WOW
WQJ
WRC
WVDHM
WXI
XG1
YFH
YUY
ZZTAW
~IA
~WT
AFJKZ
CGR
CUY
CVF
ECM
EIF
NPM
AAYXX
CITATION
7QP
7T5
7U9
H94
K9.
7X8
ID FETCH-LOGICAL-c3889-e61ff86f2416c0eed867768bc571a491315492cf209b905f2e2890a07d2111143
IEDL.DBID DR2
ISSN 1600-6135
IngestDate Fri Oct 25 09:22:26 EDT 2024
Wed Dec 18 03:28:47 EST 2024
Fri Nov 22 00:49:48 EST 2024
Sat Sep 28 08:16:30 EDT 2024
Sat Aug 24 01:08:26 EDT 2024
IsDoiOpenAccess false
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 2
Keywords liver transplantation: living donor
organ allocation
liver transplantation/hepatology
clinical research/practice
organ procurement and allocation
pediatrics
Language English
License 2019 The American Society of Transplantation and the American Society of Transplant Surgeons.
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c3889-e61ff86f2416c0eed867768bc571a491315492cf209b905f2e2890a07d2111143
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ORCID 0000-0002-6623-5561
OpenAccessLink https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ajt.15609
PMID 31550068
PQID 2344979584
PQPubID 1026366
PageCount 9
ParticipantIDs proquest_miscellaneous_2296665811
proquest_journals_2344979584
crossref_primary_10_1111_ajt_15609
pubmed_primary_31550068
wiley_primary_10_1111_ajt_15609_AJT15609
PublicationCentury 2000
PublicationDate February 2020
2020-02-00
20200201
PublicationDateYYYYMMDD 2020-02-01
PublicationDate_xml – month: 02
  year: 2020
  text: February 2020
PublicationDecade 2020
PublicationPlace United States
PublicationPlace_xml – name: United States
– name: Malden
PublicationTitle American journal of transplantation
PublicationTitleAlternate Am J Transplant
PublicationYear 2020
Publisher Elsevier Limited
Publisher_xml – sequence: 0
  name: Elsevier Limited
References 2010; 89
2018; 18
2010; 10
2015; 19
2012; 398
2019; 5
2017; 26
2017; 15
2018; 226
2004; 8
2013; 95
2017; 21
2013; 42
2015; 21
2004; 4
2016; 21
1999; 67
2018
2016; 100
2007; 83
2016; 263
2007; 13
Ersoy (10.1111/ajt.15609_bib27) 2017; 15
Venick (10.1111/ajt.15609_bib2) 2018; 226
10.1111/ajt.15609_bib21
Kasahara (10.1111/ajt.15609_bib6) 2018; 18
Magee (10.1111/ajt.15609_bib14) 2004; 4
Kasahara (10.1111/ajt.15609_bib23) 2017; 26
Moon (10.1111/ajt.15609_bib12) 2013; 42
Kiuchi (10.1111/ajt.15609_bib13) 1999; 67
10.1111/ajt.15609_bib5
Levy (10.1111/ajt.15609_bib18) 2016; 21
Sakamoto (10.1111/ajt.15609_bib8) 2018; 18
Kitajima (10.1111/ajt.15609_bib11) 2018; 18
Jafri (10.1111/ajt.15609_bib22) 2007; 13
Mandell (10.1111/ajt.15609_bib20) 2016; 100
Mizuta (10.1111/ajt.15609_bib24) 2010; 10
Kim (10.1111/ajt.15609_bib9) 2004; 8
Yoshimaru (10.1111/ajt.15609_bib25) 2017; 21
Rammohan (10.1111/ajt.15609_bib7) 2018; 18
Kanazawa (10.1111/ajt.15609_bib10) 2013; 95
Venick (10.1111/ajt.15609_bib4) 2010; 89
Ardiles (10.1111/ajt.15609_bib26) 2012; 398
Cuenca (10.1111/ajt.15609_bib3) 2017; 26
Wan (10.1111/ajt.15609_bib16) 2015; 19
Yamada (10.1111/ajt.15609_bib15) 2015; 21
Ogawa (10.1111/ajt.15609_bib17) 2007; 83
Goldaracena (10.1111/ajt.15609_bib19) 2016; 263
Kehar (10.1111/ajt.15609_bib1) 2019; 5
References_xml – volume: 10
  start-page: 2547
  year: 2010
  end-page: 2552
  article-title: Living donor liver transplantation for neonates using segment 2 monosubsegment graft
  publication-title: Am J Transplant
– volume: 398
  start-page: 79
  year: 2012
  end-page: 85
  article-title: Transplantation with hyper‐reduced liver grafts in children under 10 kg of weight
  publication-title: Langenbecks Arch Surg
– volume: 18
  start-page: 3083
  issue: 12
  year: 2018
  end-page: 3084
  article-title: Response to: “graft reduction in pediatric liver transplantation: the myth of 4?”
  publication-title: Am J Transplant
– year: 2018
  article-title: Split liver transplantation and pediatric waitlist mortality in the United States: potential for improvement
  publication-title: Transplantation
– volume: 42
  start-page: 871
  year: 2013
  end-page: 875
  article-title: Risk factors for portal vein complications after pediatric living donor liver transplantation with left‐sided grafts
  publication-title: Transplant Proc
– volume: 13
  start-page: 258
  year: 2007
  end-page: 265
  article-title: Temporary silastic mesh closure for adult liver transplantation: a safe alternative for the difficult abdomen
  publication-title: Liver Transpl
– volume: 8
  start-page: 644
  year: 2004
  end-page: 648
  article-title: Split liver transplantation: past, present and future
  publication-title: Pediatr Transplant
– volume: 226
  start-page: 355
  year: 2018
  end-page: 366
  article-title: One thousand pediatric liver transplants during thirty years: lessons learned
  publication-title: J Am Coll Surg
– volume: 95
  start-page: 750
  year: 2013
  end-page: 754
  article-title: Living‐donor liver transplantation with hyperreduced left lateral segment grafts
  publication-title: Transplantation
– volume: 18
  start-page: 2208
  year: 2018
  end-page: 2219
  article-title: Impact of graft thickness reduction of left lateral segment on outcomes following pediatric living donor liver transplantation
  publication-title: Am J Transplant
– volume: 21
  start-page: e12985
  year: 2017
  end-page: e12988
  article-title: Graft reduction using a powered stapler in pediatric living donor liver transplantation
  publication-title: Pediatr Transplant
– volume: 100
  start-page: 2362
  year: 2016
  end-page: 2371
  article-title: Early postoperative pain and its predictors in the adult to adult living donor liver transplantation cohort study
  publication-title: Transplantation
– volume: 4
  start-page: 54
  issue: Suppl 9
  year: 2004
  end-page: 71
  article-title: Pediatric transplantation
  publication-title: Am J Transplant
– volume: 263
  start-page: 979
  year: 2016
  end-page: 985
  article-title: Live donor liver transplantation with older (>/=50 years) versus younger (<50 years) donors: does age matter?
  publication-title: Ann Surg
– volume: 5
  start-page: e430
  year: 2019
  article-title: Superior outcomes and reduced wait times in pediatric recipients of living donor liver transplantation
  publication-title: Transplant Direct
– volume: 83
  start-page: 1337
  year: 2007
  end-page: 1340
  article-title: Living donor liver transplantation with reduced monosegments for neonates and small infants
  publication-title: Transplantation
– volume: 15
  start-page: 53
  year: 2017
  end-page: 56
  article-title: Effect of graft weight to recipient body weight ratio on hemodynamic and metabolic parameters in pediatric liver transplant: a retrospective analysis
  publication-title: Exp Clin Transplant
– volume: 26
  start-page: 217
  year: 2017
  end-page: 223
  article-title: Pediatric liver transplantation
  publication-title: Semin Pediatr Surg
– volume: 89
  start-page: 600
  year: 2010
  end-page: 605
  article-title: Predictors of survival following liver transplantation in infants: a single‐center analysis of more than 200 cases
  publication-title: Transplantation
– volume: 26
  start-page: 224
  year: 2017
  end-page: 232
  article-title: Pediatric living‐donor liver transplantation
  publication-title: Semin Pediatr Surg
– volume: 18
  start-page: 3081
  issue: 12
  year: 2018
  end-page: 3082
  article-title: Graft reduction in pediatric liver transplantation: the myth of 4?
  publication-title: Am J Transplant
– volume: 21
  start-page: 224
  year: 2016
  end-page: 230
  article-title: Fostering liver living donor liver transplantation
  publication-title: Curr Opin Organ Transplant
– volume: 21
  start-page: 233
  year: 2015
  end-page: 238
  article-title: Selection of living donor liver grafts for patients weighing 6 kg or less
  publication-title: Liver Transpl
– volume: 18
  start-page: 659
  year: 2018
  end-page: 668
  article-title: Living donor liver transplantation for biliary atresia: an analysis of 2085 cases in the registry of the Japanese Liver Transplantation Society
  publication-title: Am. J. Transplant
– start-page: 127
  end-page: 135
– volume: 19
  start-page: 880
  year: 2015
  end-page: 887
  article-title: Influence of graft size matching on outcomes of infantile living donor liver transplantation
  publication-title: Pediatr Transplant
– volume: 67
  start-page: 321
  year: 1999
  end-page: 327
  article-title: Impact of graft size mismatching on graft prognosis in liver transplantation from living donors
  publication-title: Transplantation
– volume: 226
  start-page: 355
  year: 2018
  ident: 10.1111/ajt.15609_bib2
  article-title: One thousand pediatric liver transplants during thirty years: lessons learned
  publication-title: J Am Coll Surg.
  doi: 10.1016/j.jamcollsurg.2017.12.042
  contributor:
    fullname: Venick
– ident: 10.1111/ajt.15609_bib21
– volume: 18
  start-page: 659
  year: 2018
  ident: 10.1111/ajt.15609_bib6
  article-title: Living donor liver transplantation for biliary atresia: an analysis of 2085 cases in the registry of the Japanese Liver Transplantation Society
  publication-title: Am. J. Transplant.
  doi: 10.1111/ajt.14489
  contributor:
    fullname: Kasahara
– volume: 8
  start-page: 644
  year: 2004
  ident: 10.1111/ajt.15609_bib9
  article-title: Split liver transplantation: past, present and future
  publication-title: Pediatr Transplant.
  doi: 10.1111/j.1399-3046.2004.00264.x
  contributor:
    fullname: Kim
– volume: 4
  start-page: 54
  issue: Suppl 9
  year: 2004
  ident: 10.1111/ajt.15609_bib14
  article-title: Pediatric transplantation
  publication-title: Am J Transplant.
  doi: 10.1111/j.1600-6143.2004.00398.x
  contributor:
    fullname: Magee
– volume: 18
  start-page: 2208
  year: 2018
  ident: 10.1111/ajt.15609_bib11
  article-title: Impact of graft thickness reduction of left lateral segment on outcomes following pediatric living donor liver transplantation
  publication-title: Am J Transplant.
  doi: 10.1111/ajt.14875
  contributor:
    fullname: Kitajima
– volume: 21
  start-page: 233
  year: 2015
  ident: 10.1111/ajt.15609_bib15
  article-title: Selection of living donor liver grafts for patients weighing 6 kg or less
  publication-title: Liver Transpl.
  doi: 10.1002/lt.24048
  contributor:
    fullname: Yamada
– volume: 21
  start-page: 224
  year: 2016
  ident: 10.1111/ajt.15609_bib18
  article-title: Fostering liver living donor liver transplantation
  publication-title: Curr Opin Organ Transplant.
  doi: 10.1097/MOT.0000000000000280
  contributor:
    fullname: Levy
– volume: 67
  start-page: 321
  year: 1999
  ident: 10.1111/ajt.15609_bib13
  article-title: Impact of graft size mismatching on graft prognosis in liver transplantation from living donors
  publication-title: Transplantation.
  doi: 10.1097/00007890-199901270-00024
  contributor:
    fullname: Kiuchi
– volume: 21
  start-page: e12985
  year: 2017
  ident: 10.1111/ajt.15609_bib25
  article-title: Graft reduction using a powered stapler in pediatric living donor liver transplantation
  publication-title: Pediatr Transplant.
  doi: 10.1111/petr.12985
  contributor:
    fullname: Yoshimaru
– volume: 19
  start-page: 880
  year: 2015
  ident: 10.1111/ajt.15609_bib16
  article-title: Influence of graft size matching on outcomes of infantile living donor liver transplantation
  publication-title: Pediatr Transplant.
  doi: 10.1111/petr.12592
  contributor:
    fullname: Wan
– volume: 5
  start-page: e430
  year: 2019
  ident: 10.1111/ajt.15609_bib1
  article-title: Superior outcomes and reduced wait times in pediatric recipients of living donor liver transplantation
  publication-title: Transplant Direct.
  doi: 10.1097/TXD.0000000000000865
  contributor:
    fullname: Kehar
– volume: 15
  start-page: 53
  year: 2017
  ident: 10.1111/ajt.15609_bib27
  article-title: Effect of graft weight to recipient body weight ratio on hemodynamic and metabolic parameters in pediatric liver transplant: a retrospective analysis
  publication-title: Exp Clin Transplant.
  contributor:
    fullname: Ersoy
– volume: 95
  start-page: 750
  year: 2013
  ident: 10.1111/ajt.15609_bib10
  article-title: Living-donor liver transplantation with hyperreduced left lateral segment grafts
  publication-title: Transplantation.
  doi: 10.1097/TP.0b013e31827a93b4
  contributor:
    fullname: Kanazawa
– volume: 398
  start-page: 79
  year: 2012
  ident: 10.1111/ajt.15609_bib26
  article-title: Transplantation with hyper-reduced liver grafts in children under 10 kg of weight
  publication-title: Langenbecks Arch Surg.
  doi: 10.1007/s00423-012-1020-y
  contributor:
    fullname: Ardiles
– volume: 26
  start-page: 217
  year: 2017
  ident: 10.1111/ajt.15609_bib3
  article-title: Pediatric liver transplantation
  publication-title: Semin Pediatr Surg.
  doi: 10.1053/j.sempedsurg.2017.07.014
  contributor:
    fullname: Cuenca
– volume: 263
  start-page: 979
  year: 2016
  ident: 10.1111/ajt.15609_bib19
  article-title: Live donor liver transplantation with older (>/=50 years) versus younger (<50 years) donors: does age matter?
  publication-title: Ann Surg.
  doi: 10.1097/SLA.0000000000001337
  contributor:
    fullname: Goldaracena
– volume: 100
  start-page: 2362
  year: 2016
  ident: 10.1111/ajt.15609_bib20
  article-title: Early postoperative pain and its predictors in the adult to adult living donor liver transplantation cohort study
  publication-title: Transplantation.
  doi: 10.1097/TP.0000000000001442
  contributor:
    fullname: Mandell
– volume: 83
  start-page: 1337
  year: 2007
  ident: 10.1111/ajt.15609_bib17
  article-title: Living donor liver transplantation with reduced monosegments for neonates and small infants
  publication-title: Transplantation.
  doi: 10.1097/01.tp.0000263340.82489.18
  contributor:
    fullname: Ogawa
– volume: 42
  start-page: 871
  year: 2013
  ident: 10.1111/ajt.15609_bib12
  article-title: Risk factors for portal vein complications after pediatric living donor liver transplantation with left-sided grafts
  publication-title: Transplant Proc.
  doi: 10.1016/j.transproceed.2010.02.059
  contributor:
    fullname: Moon
– volume: 89
  start-page: 600
  year: 2010
  ident: 10.1111/ajt.15609_bib4
  article-title: Predictors of survival following liver transplantation in infants: a single-center analysis of more than 200 cases
  publication-title: Transplantation.
  doi: 10.1097/TP.0b013e3181c5cdc1
  contributor:
    fullname: Venick
– ident: 10.1111/ajt.15609_bib5
  doi: 10.1097/TP.0000000000002249
– volume: 18
  start-page: 3081
  issue: 12
  year: 2018
  ident: 10.1111/ajt.15609_bib7
  article-title: Graft reduction in pediatric liver transplantation: the myth of 4?
  publication-title: Am J Transplant.
  doi: 10.1111/ajt.15041
  contributor:
    fullname: Rammohan
– volume: 26
  start-page: 224
  year: 2017
  ident: 10.1111/ajt.15609_bib23
  article-title: Pediatric living-donor liver transplantation
  publication-title: Semin Pediatr Surg.
  doi: 10.1053/j.sempedsurg.2017.07.008
  contributor:
    fullname: Kasahara
– volume: 18
  start-page: 3083
  issue: 12
  year: 2018
  ident: 10.1111/ajt.15609_bib8
  article-title: Response to: “graft reduction in pediatric liver transplantation: the myth of 4?”
  publication-title: Am J Transplant.
  doi: 10.1111/ajt.15085
  contributor:
    fullname: Sakamoto
– volume: 13
  start-page: 258
  year: 2007
  ident: 10.1111/ajt.15609_bib22
  article-title: Temporary silastic mesh closure for adult liver transplantation: a safe alternative for the difficult abdomen
  publication-title: Liver Transpl.
  doi: 10.1002/lt.21027
  contributor:
    fullname: Jafri
– volume: 10
  start-page: 2547
  year: 2010
  ident: 10.1111/ajt.15609_bib24
  article-title: Living donor liver transplantation for neonates using segment 2 monosubsegment graft
  publication-title: Am J Transplant.
  doi: 10.1111/j.1600-6143.2010.03274.x
  contributor:
    fullname: Mizuta
SSID ssj0017282
Score 2.4933774
Snippet Usage of “large‐for‐size” left lateral segment (LLS) liver grafts in children with high graft to recipient weight ratio (GRWR) is controversial due to concerns...
Usage of "large-for-size" left lateral segment (LLS) liver grafts in children with high graft to recipient weight ratio (GRWR) is controversial due to concerns...
SourceID proquest
crossref
pubmed
wiley
SourceType Aggregation Database
Index Database
Publisher
StartPage 504
SubjectTerms Abdomen
Child
Child, Preschool
clinical research/practice
End Stage Liver Disease - mortality
End Stage Liver Disease - surgery
Fascia
Female
Graft Survival
Hepatic artery
Humans
Infant
Liver - anatomy & histology
Liver transplantation
Liver Transplantation - methods
liver transplantation/hepatology
liver transplantation: living donor
Liver transplants
Living Donors
Male
organ allocation
organ procurement and allocation
Organ Size
Patients
Pediatrics
Portal vein
Postoperative Complications - epidemiology
Postoperative Complications - etiology
Retrospective Studies
Risk Factors
Survival
Thrombosis
Treatment Outcome
Title Pediatric living donor liver transplantation with large‐for‐size left lateral segment grafts
URI https://onlinelibrary.wiley.com/doi/abs/10.1111%2Fajt.15609
https://www.ncbi.nlm.nih.gov/pubmed/31550068
https://www.proquest.com/docview/2344979584
https://search.proquest.com/docview/2296665811
Volume 20
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1JS8QwFA7iyYsLbuNGFA9eOrRJJ23wJC6IoAdR8CDUJE1ELR2Zdi6e_An-Rn-J76XT4oIgXkqXtFleXt-S974Qsstx10XmeKC5AgNF2jRQSkaBNsIpw3MtI0wUPr8Qp9fx2c3gZorst7kwDT5E53BDzvD_a2RwpatPTK4e6z6mAWPyXsQTDOc7uuygo3DbJb_SCQIdzCM-mKAKYRRP9-ZXWfRDwfyqr3qBczJHbtumNnEmT_1xrfvm5RuK4z_7Mk9mJ4ooPWhmzgKZsuUiuet27qDFA7oaaD4shyO8sCNaeyD0QjXZSiVFHy4tMJT8_fUNlF84Vg8vlhbW1XAfc5sLWtl7dEDS-5FydbVErk-Orw5Pg8keDIHhGABlReRcKhwIemFCEKiIfydSbQZJpGIZcQ_xZhwLpZbhwDGLK5cqTHKGfYv5Mpkuh6VdJVTK3HBmYp0gyqADRcEwbZI8tVaIWKQ9stNSI3tuoDay1kSBAcr8APXIRkunbMJtVcbggzKRoEv1yHb3GPgEFz9UaYdjKMPAsAN1K4p6ZKWhb1cLRzstxBbseSr9Xn12cHblT9b-XnSdzDA00n2o9waZrkdjuwmaTK23_JT9ANJg8Fk
link.rule.ids 314,780,784,1375,27924,27925,46294,46718
linkProvider Wiley-Blackwell
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1LT9wwEB5ROLQXWtTXUlpc1EMvWSV21omlXlBbtKXAoVokLlVqOzaiRFm0m71w4ifwG_tLOuNsIihCqrhEeTjxYzyZh2c-A3wQtOsi9yIyQqOBolweaa2SyFjptRWlUQklCh8eyfFxun8yOlmBT10uTIsP0TvciDPC_5oYnBzSN7hc_26GlAesHsEasntCAV1ffvTgUbTxUljrRJGOBpIYLXGFKI6nf_W2NLqjYt7WWIPI2XsKP7vGtpEm58NFY4b28h8cx4f25hmsL3VRtttOng1YcfVz-NVv3sGqM_I2sHJaT2d04WasCVjolW4TlmpGblxWUTT5n6tr1H_xOD-7dKxyvsH7lN5csbk7JR8kO51p38xfwPHe18nncbTchiGygmKgnEy8z6VHWS9tjDKVIPBkbuwoS3SqEhFQ3qznsTIqHnnuaPFSx1nJqW-peAmr9bR2r4EpVVrBbWoyAhr0qCtYbmxW5s5Jmcp8ADsdOYqLFm2j6KwUHKAiDNAAtjpCFUuGmxccP6gyherUAN73j5FVaP1D1266wDIcbTvUuJJkAK9aAve1CDLVYmrBx0Cm-6svdvcn4WTz_4tuw-Px5PCgOPh29P0NPOFks4fI7y1YbWYL9xYVm8a8C_P3L-Bs9Ho
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1LT9wwEB5RkKpeSlEfbKHFrXroJavEzjqxekKlK6AtqiqQOFRKbcdGQJRFu9kLJ34Cv7G_pDPOJuKhShWXKA8nfown8_DMZ4APgnZd5F5ERmg0UJTLI61VEhkrvbaiNCqhROHvB3L3KN0_Hh0vwacuF6bFh-gdbsQZ4X9NDH5R-htMrs-aIaUBq0ewkkquCDh_52ePHUX7LoWlTpToaB-J0QJWiMJ4-ldvC6N7GuZthTVInPEq_Ora2gaanA_njRnayzswjg_szDN4utBE2XY7ddZgydXP4Xe_dQerTsnXwMpJPZnShZuyJiChV7pNV6oZOXFZRbHkf66uUfvF4-z00rHK-QbvU3JzxWbuhDyQ7GSqfTN7AUfjL4efd6PFJgyRFRQB5WTifS49SnppY5SoBIAnc2NHWaJTlYiA8WY9j5VR8chzR0uXOs5KTn1LxUtYrie1WwemVGkFt6nJCGbQo6ZgubFZmTsnZSrzAbzvqFFctFgbRWej4AAVYYAGsNnRqViw26zg-EGVKVSmBvCuf4yMQqsfunaTOZbhaNmhvpUkA3jV0revRZChFlMLPgYq_bv6Ynv_MJy8_v-iW_D4x864-LZ38HUDnnAy2EPY9yYsN9O5e4NaTWPehtn7Fxaf8yk
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Pediatric+living+donor+liver+transplantation+with+large-for-size+left+lateral+segment+grafts&rft.jtitle=American+journal+of+transplantation&rft.au=Goldaracena%2C+Nicolas&rft.au=Echeverri%2C+Juan&rft.au=Kehar%2C+Mohit&rft.au=DeAngelis%2C+Maria&rft.date=2020-02-01&rft.issn=1600-6135&rft.volume=20&rft.issue=2&rft.spage=504&rft.epage=512&rft_id=info:doi/10.1111%2Fajt.15609&rft.externalDBID=n%2Fa&rft.externalDocID=10_1111_ajt_15609
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1600-6135&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1600-6135&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1600-6135&client=summon