Sodium-Proton Exchange and Primary Hypertension: An Update

• Published in: Hypertension (Dallas, Tex. 1979) Vol. 26; no. 4; pp. 649 - 655
• Main Authors: Siffert, Winfried, Dusing, Rainer
• Format: Journal Article
• Language: English
• Published: Philadelphia, PA American Heart Association, Inc 01.10.1995; Hagerstown, MD Lippincott
• Subjects: Animals; Arterial hypertension. Arterial hypotension; Biological and medical sciences; Blood and lymphatic vessels; Cardiology. Vascular system; Cell Division; Cell Line, Transformed - metabolism; Clinical manifestations. Epidemiology. Investigative techniques. Etiology; Humans; Hypertension - metabolism; Hypertension - pathology; Intracellular Membranes - metabolism; Medical sciences; Phenotype; Sodium-Hydrogen Exchangers - metabolism; Human; Hypertension; Cell culture; Regulation(control); Pathophysiology; Sodium; Proton; Cardiovascular disease; Ion exchange

An enhancement of sodium-proton exchange in blood cells of patients with primary hypertension has been described by various investigators. The present review summarizes some of the most recent findings regarding the enhanced sodium-proton exchanger activity in primary hypertension and discusses the...