Antithrombin‐III mitigates thrombin‐mediated endothelial cell contraction and sickle red blood cell adhesion in microscale flow - Wulftange, William J.; Kucukal, Erdem; Man, Yuncheng; An, Ran; Monchamp, Karamoja; Sevrain, Charlotte D.; Dashora, Himanshu R.; Owusu‐Ansah, Amma T.; Bode, Allison; Ilich, Anton; Little, Jane A.; Key, Nigel S.; et al. (British journal of haematology, 2022)
Keywords: Anemia, Sickle Cell; Anticoagulants - pharmacology; Antithrombin; Antithrombins - metabolism; Antithrombins - pharmacology; Blood; Cell Adhesion; Cell adhesion & migration; Cell adhesion molecules; Cell surface; coagulation; Cytology; Endothelial Cells; Endothelium; Endothelium, Vascular - metabolism; Erythrocytes; Hematology; Hemoglobin; Humans; Microfluidics; Proteinase inhibitors; Serine proteinase; Sickle cell disease; Thrombin; Thrombin - metabolism; Thrombin - pharmacology; vascular endothelium; Von Willebrand factor; antithrombin; vascular endothelium; thrombin; coagulation; microfluidics; sickle cell disease