Functional profile of oral plaque microbiome: Further insight into the bidirectional relationship between type 2 diabetes and periodontitis

• Published in: Molecular oral microbiology Vol. 39; no. 2; pp. 62 - 79
• Main Authors: Favale, Nicoletta, Farina, Roberto, Carrieri, Alberto, Simonelli, Anna, Severi, Mattia, Sabbioni, Silvia, Trombelli, Leonardo, Scapoli, Chiara
• Format: Journal Article
• Language: English
• Published: Denmark Wiley Subscription Services, Inc 01.04.2024
• Subjects: adipocytokine signaling pathways; Adipose tissue; Amino acids; BCAA; Biosynthesis; Chromatin; Comorbidity; Dental Plaque; Diabetes; Diabetes mellitus (non-insulin dependent); Diabetes Mellitus, Type 2 - complications; Dysbacteriosis; Endotoxemia; Epigenetics; Ferroptosis; Gum disease; Homeostasis; Humans; Immune response; Immune system; Inflammation; Intestinal microflora; Lipopolysaccharides; Metabolic pathways; Metabolism; Metagenomics; Microbiomes; Microbiota - genetics; Microorganisms; Nucleotides; oral microbiome; Peptidoglycans; Periodontal Diseases; Periodontitis; Shotguns; type 2 diabetes; ferroptosis; type 2 diabetes; adipocytokine signaling pathways; inflammation; metagenomics; endotoxemia; periodontitis; oral microbiome; BCAA

Increasing evidence support the association between the oral microbiome and human systemic diseases. This association may be attributed to the ability of many oral microbes to influence the inflammatory microenvironment. Herein, we focused our attention on the bidirectional relationship between peri...