Patient‐Specific Analysis of Neural Activation During Spinal Cord Stimulation for Pain

• Published in: Neuromodulation (Malden, Mass.) Vol. 23; no. 5; pp. 572 - 581
• Main Authors: Lempka, Scott F., Zander, Hans J., Anaya, Carlos J., Wyant, Alexandria, Ozinga, John G., Machado, Andre G.
• Format: Journal Article
• Language: English
• Published: Hoboken, USA John Wiley & Sons, Inc 01.07.2020; Elsevier Limited
• Subjects: Anatomy; Axons; Axons - physiology; Chronic pain; Chronic Pain - therapy; Computational neuroscience; Computer Simulation; Electrodes; failed back surgery syndrome; Humans; Mathematical models; Models, Neurological; Pain; Pain Measurement; Spinal cord; Spinal Cord - physiology; Spinal Cord Stimulation; failed back surgery syndrome; computer simulation; spinal cord stimulation; Chronic pain

Objective Despite the widespread use of spinal cord stimulation (SCS) for chronic pain management, its neuromodulatory effects remain poorly understood. Computational models provide a valuable tool to study SCS and its effects on axonal pathways within the spinal cord. However, these models must inc...