CLEC5A expression can be triggered by spike glycoprotein and may be a potential target for COVID‐19 therapy - Machado, Thiago L.; Santos, Alanna C.; Azamor, Tamiris; Silva, Andrea M. V.; Pimenta, Vanessa R.; Tubarão, Luciana N.; Silva, Alexandre dos Santos; Flores Rodrigues, Daniela Del Rosário; Müller, Rodrigo; Pinto, Marcelo A.; Villar, Livia M.; Bom, Ana P. A.; et al. (Journal of medical virology, 2023)
Keywords: Antibodies, Monoclonal; Bacterial diseases; Binding sites; Cell activation; CLEC5A; CLEC5A protein; Coronaviruses; COVID-19; COVID-19 Drug Treatment; Cytokines; Gene expression; Glycoproteins; Hamsters; Humans; Immune response; Immune system; Immunology; immunotherapy; Infections; Inflammation; Lectins, C-Type - genetics; Leukocytes (neutrophilic); Molecular interactions; Monoclonal antibodies; Monocytes; N-Acetylglucosamine; Receptors; Receptors, Cell Surface - genetics; Respiratory diseases; Respiratory function; SARS-CoV-2; Severe acute respiratory syndrome; Severe acute respiratory syndrome coronavirus 2; Spike glycoprotein; Spike Glycoprotein, Coronavirus; spike protein; Vaccines; Viral diseases; Virology; COVID-19; monocytes; CLEC5A; immunotherapy; spike protein