Inhibition of PIKFYVE kinase interferes ESCRT pathway to suppress RNA virus replication - Luo, Zhen; Liang, Yicong; Tian, Mingfu; Ruan, Zhihui; Su, Rui; Shereen, Muhammad Adnan; Yin, Jialing; Wu, Kailang; Guo, Jun; Zhang, Qiwei; Li, Yongkui; Wu, Jianguo (Journal of medical virology, 2023)
Keywords: Antiviral agents; Antiviral drugs; antiviral therapy; DNA viruses; endosomal sorting complex required for transport (ESCRT); Endosomal Sorting Complexes Required for Transport - genetics; Endosomal Sorting Complexes Required for Transport - metabolism; Enteroviruses; enveloped RNA viruses; Hepatitis B; Humans; Infections; Inflammation; Interferon; Kinases; nonenveloped RNA viruses; Phosphatidylinositol 3-Kinases; phosphoinositide kinase FYVE finger containing (PIKFYVE); Poliovirus - genetics; Replication; Ribonucleic acid; RNA; RNA virus replication; RNA viruses; Stomatitis; Vector-borne diseases; Virology; Virus Replication - physiology; Viruses; Zika virus; Zika Virus - genetics; Zika Virus Infection; phosphoinositide kinase FYVE finger containing (PIKFYVE); RNA virus replication; enveloped RNA viruses; antiviral therapy; nonenveloped RNA viruses; endosomal sorting complex required for transport (ESCRT)