Effects of P2Y12 receptor inhibition with or without aspirin on hemostatic system activation: a randomized trial in healthy subjects - Traby, L.; Kollars, M.; Kaider, A.; Eichinger, S.; Wolzt, M.; Kyrle, P. A. (Journal of thrombosis and haemostasis, 2016)
Keywords: Acute coronary syndromes; Adenosine - administration & dosage; Adenosine - adverse effects; Adenosine - analogs & derivatives; Adolescent; Adult; Angina pectoris; Area Under Curve; Aspirin; Aspirin - administration & dosage; Aspirin - adverse effects; Austria; beta-Thromboglobulin - metabolism; Biomarkers - blood; Bleeding Time; Blood Platelets - drug effects; Blood Platelets - metabolism; clopidogrel; Confidence intervals; Double-Blind Method; Healthy Volunteers; Heart attacks; Hemostasis - drug effects; Humans; Male; Middle Aged; Peptide Fragments - blood; platelet aggregation inhibitors; Platelet Aggregation Inhibitors - administration & dosage; Platelet Aggregation Inhibitors - adverse effects; Predictive Value of Tests; Prothrombin; Purinergic P2Y Receptor Antagonists - administration & dosage; Purinergic P2Y Receptor Antagonists - adverse effects; Receptors, Purinergic P2Y12 - drug effects; Receptors, Purinergic P2Y12 - metabolism; ROC Curve; ticagrelor; Ticlopidine - administration & dosage; Ticlopidine - adverse effects; Ticlopidine - analogs & derivatives; Time Factors; Young Adult; clopidogrel; aspirin; ticagrelor; platelet aggregation inhibitors; acute coronary syndromes