Biosignatures of defective sebaceous gland activity in sebum‐rich and sebum‐poor skin areas in adult atopic dermatitis

• Published in: Experimental dermatology Vol. 33; no. 3; pp. e15066 - n/a
• Main Authors: Cavallo, Alessia, Camera, Emanuela, Bottillo, Grazia, Maiellaro, Miriam, Truglio, Mauro, Marini, Federico, Chavagnac‐Bonneville, Marlène, Fauger, Aurélie, Perrier, Eric, Pigliacelli, Flavia, Picardo, Mauro, Cristaudo, Antonio, Mariano, Maria
• Format: Journal Article
• Language: English
• Published: Denmark Wiley Subscription Services, Inc 01.03.2024
• Subjects: aminoacids; Atopic dermatitis; cholesterol; Dermatitis; epidermal lipids; fatty acids; fatty alcohols; Gender; Lipids; Permeability; Phenotypes; sapienate; Sebaceous gland; Squalene; Stratum corneum; epidermal lipids; fatty alcohols; sebaceous gland; fatty acids; aminoacids; cholesterol; sapienate; squalene

Atopic dermatitis (AD) is a composite disease presenting disruption of the skin permeability barrier (SPB) in the stratum corneum (SC). Recent evidence supports derangement of the sebaceous gland (SG) activity in the AD pathomechanisms. The objective of this study was to delineate profiles of both s...