Prepulse inhibition of the blink reflex is abnormal in functional movement disorders

• Published in: Movement disorders Vol. 34; no. 7; pp. 1022 - 1030
• Main Authors: Hanzlíková, Zuzana, Kofler, Markus, Slovák, Matěj, Věchetová, Gabriela, Fečíková, Anna, Kemlink, David, Sieger, Tomáš, Růžička, Evžen, Valls‐Solé, Josep, Edwards, Mark J., Serranová, Tereza
• Format: Journal Article
• Language: English
• Published: Hoboken, USA John Wiley & Sons, Inc 01.07.2019; Wiley Subscription Services, Inc
• Subjects: Adult; Anxiety; attention; Blink reflex; Blinking - physiology; Electric Stimulation - methods; Electrical stimuli; Female; Fibromyalgia; Fingers - physiopathology; functional movement disorders; Humans; Information processing; Male; Mental depression; Middle Aged; Movement disorders; Movement Disorders - physiopathology; Neural coding; Neural Inhibition - physiology; Pain; prepulse inhibition; Prepulse Inhibition - physiology; Reflex, Startle - physiology; Sensory integration; Standard deviation; blink reflex; sensory integration; attention; functional movement disorders; prepulse inhibition

Background Patients with functional movement disorders also typically have functional somatic symptoms, including pain, fatigue, and sensory disturbance. A potentially unifying mechanism for such symptoms is a failure in processing of sensory inputs. Prepulse inhibition is a neurophysiological metho...