Pulmonary artery and lung parenchymal growth following early versus delayed stent interventions in a swine pulmonary artery stenosis model

• Published in: Catheterization and cardiovascular interventions Vol. 96; no. 7; pp. 1454 - 1464
• Main Authors: Pewowaruk, Ryan, Hermsen, Joshua, Johnson, Cody, Erdmann, Alexandra, Pettit, Kevin, Aesif, Scott, Ralphe, J. Carter, Francois, Christopher J., Roldán‐Alzate, Alejandro, Lamers, Luke
• Format: Journal Article
• Language: English
• Published: Hoboken, USA John Wiley & Sons, Inc 01.12.2020; Wiley Subscription Services, Inc
• Subjects: Alveoli; Animals; Blood flow; Catheterization; Catheters; Computed tomography; congenital heart disease; Disease Models, Animal; Endovascular Procedures - instrumentation; Heart; Hemodynamics; Implants; Lung - blood supply; Lung - growth & development; Lungs; Magnetic resonance imaging; Male; pediatric interventions; Pulmonary arteries; Pulmonary artery; Pulmonary Artery - growth & development; pulmonary artery stenting; Stenosis; Stenosis, Pulmonary Artery - diagnostic imaging; Stenosis, Pulmonary Artery - physiopathology; Stenosis, Pulmonary Artery - therapy; Stents; Sus scrofa; Time Factors; Time-to-Treatment; Veins & arteries; congenital heart disease; pediatric interventions; pulmonary artery stenting

Objectives Compare lung parenchymal and pulmonary artery (PA) growth and hemodynamics following early and delayed PA stent interventions for treatment of unilateral branch PA stenosis (PAS) in swine. Background How the pulmonary circulation remodels in response to different durations of hypoperfusio...