Antithrombotic treatment with direct‐acting oral anticoagulants in patients with splanchnic vein thrombosis and cirrhosis

• Published in: Liver international Vol. 37; no. 5; pp. 694 - 699
• Main Authors: De Gottardi, Andrea, Trebicka, Jonel, Klinger, Christoph, Plessier, Aurélie, Seijo, Susana, Terziroli, Benedetta, Magenta, Lorenzo, Semela, David, Buscarini, Elisabetta, Langlet, Philippe, Görtzen, Jan, Puente, Angela, Müllhaupt, Beat, Navascuès, Carmen, Nery, Filipe, Deltenre, Pierre, Turon, Fanny, Engelmann, Cornelius, Arya, Rupen, Caca, Karel, Peck‐Radosavljevic, Markus, Leebeek, Frank W. G., Valla, Dominique, Garcia‐Pagan, Juan Carlos, Grønbæk, Henning, Beer, Jürg‐Hans, Genescà, Joan, Hidalgo, Canete, Vila, Carmen, Mihailovic, Jelena, Piscaglia, Fabio, Lasser, Luc, Fernandez‐Bermejo, Miguel, Procopet, Bogdan, Schouten, Jeoffrey, Spahr, Laurent, Sanchez, José Louis, Zipprich, Alexander, Sekhar, Mallika, Hernandez‐Guerra, Manuel, Laguna, La, Nevens, Frederik, Ferreira, Carlos Noronha, Heneghan, Michael, Albillos, Agustin, Llop, Elba, Dell'Era, Alessandra, La Mura, Vincenzo, Primignani, Massimo, Senzolo, Marco, Escarda, Ana, Mallorca, Palma, Riggio, Oliviero, Murad, Sarwa Darwish, Haas, Stephan, Bureau, Christophe, Berenguer, Marina
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.05.2017
• Subjects: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Antagonists; Anticoagulants; Anticoagulants - adverse effects; Anticoagulants - therapeutic use; anticoagulation; Atrial Fibrillation - drug therapy; Bleeding; Budd‐Chiari syndrome; Cirrhosis; Clinical trials; Coagulation; Complications; Consortia; Data collection; Demographics; Europe; Female; Fibrillation; Gastrointestinal Hemorrhage - chemically induced; Heparin; Humans; Kidneys; Liver; Liver cirrhosis; Liver Cirrhosis - complications; Liver diseases; Male; Medical research; Middle Aged; Molecular weight; Patients; Portal vein; portal vein thrombosis; Renal function; Side effects; Splanchnic Circulation - physiology; Switching; Thromboembolism; Thrombosis; Venous Thrombosis - drug therapy; Vitamin K; Vitamin K - antagonists & inhibitors; Young Adult; Budd-Chiari syndrome; portal vein thrombosis; cirrhosis; anticoagulation

Background Direct‐acting oral anticoagulants (DOACs) are used in patients with splanchnic vein thrombosis (SVT) and cirrhosis, but evidence for safety and efficacy in this setting is limited. Our aim was to identify indications and reasons for starting or switching to DOACs and to report adverse eff...