CISD1 in association with obesity‐associated dysfunctional adipogenesis in human visceral adipose tissue

• Published in: Obesity (Silver Spring, Md.) Vol. 24; no. 1; pp. 139 - 147
• Main Authors: Moreno‐Navarrete, José María, Moreno, María, Ortega, Francisco, Sabater, Mònica, Xifra, Gemma, Ricart, Wifredo, Fernández‐Real, José Manuel
• Format: Journal Article
• Language: English
• Published: United States Blackwell Publishing Ltd 01.01.2016
• Subjects: Adipocytes; Adipogenesis - genetics; Adipose Tissue - metabolism; Adult; Aged; Bariatric Surgery; Biopsy; Biosynthesis; Body fat; Body Mass Index; Cell Differentiation - genetics; Cells, Cultured; Cohort Studies; Female; Gastrointestinal surgery; Gene Expression; Glucose; Homeostasis; Hospitals; Humans; Insulin; Insulin resistance; Insulin Resistance - genetics; Intra-Abdominal Fat - metabolism; Intra-Abdominal Fat - pathology; Iron; Male; Metabolism; Middle Aged; Mitochondrial Proteins - genetics; Mitochondrial Proteins - metabolism; Obesity; Obesity - genetics; Obesity - metabolism; Obesity - pathology; Obesity - surgery; Proteins; Sulfur

Objective To investigate CISD1 mRNA and protein in human adipose tissue in association with obesity and adipogenesis. Methods Subcutaneous (SAT) and visceral (VAT) adipose tissue CISD1 gene expression (real‐time PCR) and protein (Western blot) levels were investigated in human adipose tissue and dur...