Deferasirox induces cyclin D1 degradation and apoptosis in mantle cell lymphoma in a reactive oxygen species‐ and GSK3β‐dependent mechanism - Samara, Aladin; Shapira, Saar; Lubin, Ido; Shpilberg, Ofer; Avigad, Smadar; Granot, Galit; Raanani, Pia (British journal of haematology, 2021)
Keywords: 1-Phosphatidylinositol 3-kinase; AKT protein; Apoptosis; Cell cycle; Cell proliferation; Chelating agents; Cyclin D1; Cytotoxicity; deferasirox; DNA damage; Glycogen; Glycogen synthase kinase 3; GSK3β; Hematology; Iron; Kinases; Lymphoma; Malignancy; Mantle cell lymphoma; Oxidative stress; Phosphorylation; Proteolysis; Reactive oxygen species; ROS; Tumors; GSK3β; mantle cell lymphoma; cyclin D1; deferasirox; ROS