Safety of prothrombin complex concentrate in healthy subjects
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| Published in | British journal of haematology Vol. 176; no. 4; pp. 664 - 666 |
|---|---|
| Main Authors | , , , , |
| Format | Journal Article |
| Language | English |
| Published |
England
Blackwell Publishing Ltd
01.02.2017
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| Subjects | |
| Online Access | Get full text |
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| Author | Coppens, Michiel Picchi, Chiara Trinchero, Alice Barco, Stefano Middeldorp, Saskia |
|---|---|
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| Cites_doi | 10.1160/TH07-05-0367 10.1111/jth.13115 10.1016/j.thromres.2015.07.012 10.1160/TH11-01-0052 10.1161/CIRCULATIONAHA.114.013445 10.1111/jth.12599 10.1111/bjh.13821 10.1182/blood.V124.21.345.345 10.1161/CIRCULATIONAHA.111.029017 10.1016/j.annemergmed.2015.04.036 |
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| Keywords | anticoagulants meta-analysis bleeding disorders reversal thrombosis prothrombin complex concentrate |
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| References | 2015; 13 2011; 124 2011; 106 2014; S124 2007; 98 2015; 136 2014; 12 2016; 67 2015; 131 2016; 172 e_1_2_3_2_1 e_1_2_3_6_1 e_1_2_3_5_1 e_1_2_3_4_1 e_1_2_3_3_1 Perlstein I. (e_1_2_3_10_1) 2014; 124 e_1_2_3_9_1 e_1_2_3_8_1 e_1_2_3_7_1 e_1_2_3_11_1 |
| References_xml | – volume: 136 start-page: 825 year: 2015 end-page: 831 article-title: The impact of a three‐factor prothrombin complex concentrate on the anticoagulatory effects of the factor Xa inhibitor edoxaban publication-title: Thrombosis Research – volume: 13 start-page: 1799 year: 2015 end-page: 1805 article-title: In vivo increase in thrombin generation by four‐factor prothrombin complex concentrate in apixaban‐treated healthy volunteers publication-title: Journal of Thrombosis and Haemostasis – volume: 124 start-page: 1573 year: 2011 end-page: 1579 article-title: Reversal of rivaroxaban and dabigatran by prothrombin complex concentrate: a randomized, placebo‐controlled, crossover study in healthy subjects publication-title: Circulation – volume: 67 start-page: 96 year: 2016 end-page: 105 article-title: Thromboembolic events after vitamin K antagonist reversal with 4‐factor prothrombin complex concentrate: exploratory analyses of two randomized, plasma‐controlled studies publication-title: Annals of Emergency Medicine – volume: 98 start-page: 790 year: 2007 end-page: 797 article-title: Pharmacokinetics of Beriplex P/N prothrombin complex concentrate in healthy volunteers publication-title: Thrombosis and Haemostasis – volume: 172 start-page: 255 year: 2016 end-page: 261 article-title: In vivo reversal of the anticoagulant effect of rivaroxaban with four‐factor prothrombin complex concentrate publication-title: British Journal of Haematology – volume: 12 start-page: 1428 year: 2014 end-page: 1436 article-title: Comparison of three‐factor and four‐factor prothrombin complex concentrates regarding reversal of the anticoagulant effects of rivaroxaban in healthy volunteers publication-title: Journal of Thrombosis and Haemostasis – volume: S124 start-page: 345 year: 2014 article-title: Reversal of apixaban anticoagulation by 4‐factor prothrombin complex concentrates in healthy subjects publication-title: Blood – volume: 106 start-page: 429 year: 2011 end-page: 438 article-title: Safety of prothrombin complex concentrates for rapid anticoagulation reversal of vitamin K antagonists. A meta‐analysis publication-title: Thrombosis and Haemostasis – volume: 131 start-page: 82 year: 2015 end-page: 90 article-title: Edoxaban effects on bleeding following punch biopsy and reversal by a 4‐factor prothrombin complex concentrate publication-title: Circulation – ident: e_1_2_3_9_1 doi: 10.1160/TH07-05-0367 – ident: e_1_2_3_4_1 doi: 10.1111/jth.13115 – ident: e_1_2_3_3_1 doi: 10.1016/j.thromres.2015.07.012 – ident: e_1_2_3_5_1 doi: 10.1160/TH11-01-0052 – ident: e_1_2_3_11_1 doi: 10.1161/CIRCULATIONAHA.114.013445 – ident: e_1_2_3_7_1 doi: 10.1111/jth.12599 – ident: e_1_2_3_2_1 doi: 10.1111/bjh.13821 – volume: 124 start-page: 345 year: 2014 ident: e_1_2_3_10_1 article-title: Reversal of apixaban anticoagulation by 4‐factor prothrombin complex concentrates in healthy subjects publication-title: Blood doi: 10.1182/blood.V124.21.345.345 – ident: e_1_2_3_6_1 doi: 10.1161/CIRCULATIONAHA.111.029017 – ident: e_1_2_3_8_1 doi: 10.1016/j.annemergmed.2015.04.036 |
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| SubjectTerms | anticoagulants bleeding disorders Blood Coagulation - drug effects Blood Coagulation Factors - administration & dosage Blood Coagulation Factors - adverse effects Healthy Volunteers Hematology Hemorrhage - drug therapy Hemorrhage - etiology Humans meta‐analysis Prothrombin prothrombin complex concentrate reversal thrombosis |
| Title | Safety of prothrombin complex concentrate in healthy subjects |
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