In vitro benzo[a]pyrene diol epoxide‐induced DNA damage and chromosomal aberrations in primary lymphocytes, smoking, and risk of squamous cell carcinoma of the head and neck - Xiong, Ping; Hu, Zhibin; Li, Chunying; Wang, Li‐E; El‐Naggar, Adel K.; Sturgis, Erich M.; Wei, Qingyi (International journal of cancer, 2007)
Keywords: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide - toxicity; Adult; Aged; benzo[a]pyrene diol epoxide; Biological and medical sciences; cancer susceptibility; Carcinogens - toxicity; Carcinoma, Squamous Cell - epidemiology; Carcinoma, Squamous Cell - etiology; Carcinoma, Squamous Cell - genetics; Case-Control Studies; Chromosome Aberrations - chemically induced; Comet Assay; DNA Damage - drug effects; DNA Repair; Female; Genetic Predisposition to Disease; gene–environment interaction; Head and Neck Neoplasms - epidemiology; Head and Neck Neoplasms - etiology; Head and Neck Neoplasms - genetics; Humans; Lymphocytes; Male; Medical sciences; Middle Aged; mutagen sensitivity; Mutagens - toxicity; Odds Ratio; Risk Assessment; Risk Factors; Smoking - adverse effects; Texas - epidemiology; Tobacco, tobacco smoking; Toxicology; Tumors; Texas; Chromosomal aberration; Diol; cancer susceptibility; Tobacco smoking; gene-environment interaction; Malignant tumor; Mutagen; Epidemiology; In vitro; Comet assay; benzo[a]pyrene diol epoxide; Sensitivity; Cancerology; Genotype environment interaction; Epoxide; Risk factor; Primary; ENT disease; Head and neck squamous cell carcinoma; Head and neck cancer; mutagen sensitivity; Lesion; Lymphocyte; Cancer