Precision Dosing for Tacrolimus Using Genotypes and Clinical Factors in Kidney Transplant Recipients of European Ancestry - Al-Kofahi, Mahmoud; Oetting, William S; Schladt, David P; Remmel, Rory P; Guan, Weihua; Wu, Baolin; Dorr, Casey R; Mannon, Roslyn B; Matas, Arthur J; Israni, Ajay K; Jacobson, Pamala A (Journal of clinical pharmacology, 2021)
Keywords: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Comorbidity; Cytochrome P-450 CYP3A - genetics; Drug Interactions; Female; Genotype; Humans; Immunosuppressive Agents - administration & dosage; Immunosuppressive Agents - pharmacokinetics; Kidney Transplantation; Male; Metabolic Clearance Rate; Middle Aged; Models, Biological; Tacrolimus - administration & dosage; Tacrolimus - pharmacokinetics; Transplant Recipients; White People; Young Adult; kidney transplant; genomics; pharmacogenomics; tacrolimus; population pharmacokinetics