Forecasting the long‐term impact of COVID‐19 on hepatitis C elimination plans in Italy: A mathematical modelling approach

• Published in: Liver international Vol. 43; no. 12; pp. 2615 - 2624
• Main Authors: Kondili, Loreta A., Andreoni, Massimo, Aghemo, Alessio, Mastroianni, Claudio Maria, Merolla, Rocco, Gallinaro, Valentina, D'Offizi, Gianpiero, Craxì, Antonio
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.12.2023
• Subjects: Antiviral Agents - therapeutic use; Carcinoma, Hepatocellular; Cirrhosis; Coronaviruses; COVID-19; Fatalities; HCV; Hepacivirus; Hepatitis C; Hepatitis C - diagnosis; hepatitis C infection; Hepatitis C, Chronic - drug therapy; Hepatocellular carcinoma; Humans; Italy - epidemiology; Liver; Liver cancer; Liver Cirrhosis - drug therapy; Liver diseases; Liver Neoplasms - drug therapy; Markov chain; Markov chains; Mathematical analysis; mathematical modelling; Mathematical models; Monte Carlo probabilistic analysis; Pandemics; Viral diseases; Italy; COVID-19; Markov chain; HCV; mathematical modelling; hepatitis C infection; Monte Carlo probabilistic analysis

Background Italy has a high HCV prevalence, and despite the approval of a dedicated fund for ‘Experimental screening’ for 2 years, screening has not been fully implemented. We aimed to evaluate the long‐term impact of the persisting delay in HCV elimination after the Coronavirus disease 2019 (COVID‐...