Preventive exercise and physical rehabilitation promote long‐term potentiation‐like plasticity expression in patients with multiple sclerosis

• Published in: European journal of neurology Vol. 31; no. 3; pp. e16071 - n/a
• Main Authors: Stampanoni Bassi, Mario, Gilio, Luana, Buttari, Fabio, Dolcetti, Ettore, Bruno, Antonio, Galifi, Giovanni, Azzolini, Federica, Borrelli, Angela, Mandolesi, Georgia, Gentile, Antonietta, De Vito, Francesca, Musella, Alessandra, Simonelli, Ilaria, Centonze, Diego, Iezzi, Ennio
• Format: Journal Article
• Language: English
• Published: England John Wiley & Sons, Inc 01.03.2024
• Subjects: Autoimmune diseases; Evoked Potentials, Motor - physiology; Exercise; Humans; Long-term potentiation; Long-Term Potentiation - physiology; Multiple Sclerosis; multiple sclerosis (MS); Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Neurology; Neuronal Plasticity - physiology; Physical activity; Physical exercise; Physical fitness; physical rehabilitation; Physical training; Plasticity; Rehabilitation; Stimulation; Synaptic plasticity; Transcranial Magnetic Stimulation; transcranial magnetic stimulation (TMS); multiple sclerosis (MS); physical rehabilitation; exercise; synaptic plasticity; transcranial magnetic stimulation (TMS)

Background and purpose Loss of long‐term potentiation (LTP) expression has been associated with a worse disease course in relapsing–remitting multiple sclerosis (RR‐MS) and represents a pathophysiological hallmark of progressive multiple sclerosis (PMS). Exercise and physical rehabilitation are the...