Spectral diffusion analysis of kidney intravoxel incoherent motion MRI in healthy volunteers and patients with renal pathologies

• Published in: Magnetic resonance in medicine Vol. 85; no. 6; pp. 3085 - 3095
• Main Authors: Stabinska, Julia, Ljimani, Alexandra, Zöllner, Helge Jörn, Wilken, Enrica, Benkert, Thomas, Limberg, Juliane, Esposito, Irene, Antoch, Gerald, Wittsack, Hans‐Jörg
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.06.2021
• Subjects: Blood flow; Blood vessels; Diffusion; Diffusion rate; DWI; Fibrosis; Human motion; IVIM; kidney; Kidney cancer; Kidney diseases; Kidney transplantation; Kidneys; Magnetic resonance imaging; Neuroimaging; NNLS; Renal cell carcinoma; Renal cortex; Spectra; tubular volume fraction; kidney; IVIM; NNLS; tubular volume fraction; DWI

Purpose To assess the feasibility of measuring tubular and vascular signal fractions in the human kidney using nonnegative least‐square (NNLS) analysis of intravoxel incoherent motion data collected in healthy volunteers and patients with renal pathologies. Methods MR imaging was performed at 3 Tesl...