Unravelling the complexity and redundancy of carbon catabolic repression in Pseudomonas fluorescens SBW25

• Published in: Molecular microbiology Vol. 105; no. 4; pp. 589 - 605
• Main Authors: Liu, Yunhao, Gokhale, Chaitanya S., Rainey, Paul B., Zhang, Xue‐Xian
• Format: Journal Article
• Language: English
• Published: England Blackwell Publishing Ltd 01.08.2017
• Subjects: Bacteria; Bacterial Proteins - metabolism; Biochemical analysis; Carbon; Carbon - metabolism; Carbon sources; Catabolism; Catabolite repression; Catabolite Repression - genetics; Catabolite Repression - physiology; Complexity; Deactivation; Empirical analysis; Fitness; Gene Expression Regulation, Bacterial - genetics; Genes; Inactivation; Mathematical models; Nutrient concentrations; Nutrient sources; Pseudomonas fluorescens; Pseudomonas fluorescens - genetics; Pseudomonas fluorescens - metabolism; Redundancy; Reproductive fitness; RNA, Bacterial - metabolism; RNA, Messenger - metabolism; RNA, Untranslated - metabolism; Substrates; Suppressors; Transcription; Transposon mutagenesis; Xylose

Summary The two‐component system CbrAB is the principal regulator for cellular metabolic balance in Pseudomonas fluorescens SBW25 and is necessary for growth on many substrates including xylose. To understand the regulatory linkage between CbrAB and genes for xylose utilization (xut), we performed t...