Dynamic changes in transcriptome during orthodontic tooth movement

• Published in: Orthodontics & craniofacial research Vol. 26; no. S1; pp. 73 - 81
• Main Authors: Liu, Jia, Chen, Po‐Jung, Mehta, Shivam, Dutra, Eliane H., Yadav, Sumit
• Format: Journal Article
• Language: English
• Published: England Wiley Subscription Services, Inc 01.12.2023
• Subjects: Alveolar bone; Animal models; Bone remodeling; Gene expression; Genomes; Hypoxia; Maxilla; Molars; Next-generation sequencing; orthodontic tooth movement; Orthodontics; Principal components analysis; RNA sequencing; Teeth; Transciptome; Transcriptomes; RNA sequencing; Transciptome; orthodontic tooth movement

Objectives The objective of this study was to determine global changes in gene expression with next generation sequencing (NGS) in order to assess the biological effects of orthodontic tooth movement (OTM) on alveolar bone in a rat model. Materials and Methods Thirty‐five Wistar rats (age 14 weeks)...