High‐resolution manometry reveals different effect of polyethylene glycol, bisacodyl, and prucalopride on colonic motility in healthy subjects: An acute, open label, randomized, crossover, reader‐blinded study with potential clinical implications - Corsetti, Maura; Thys, Alexander; Harris, Alexander; Pagliaro, Giuseppe; Deloose, Eveline; Demedts, Ingrid; Tack, Jan (Neurogastroenterology and motility, 2021)
Keywords: Adult; Benzofurans - pharmacology; bisacodyl; Bisacodyl - pharmacology; Colon; Colon - drug effects; colon motility; Constipation; Cross-Over Studies; Female; Gastrointestinal Motility - drug effects; Healthy Volunteers; high‐resolution manometry; Humans; Laxatives - pharmacology; Male; Manometry; Motility; Oral administration; Patients; PEG; Peristalsis - drug effects; Placebos; Polyethylene glycol; Polyethylene Glycols - pharmacology; prucalopride; Single-Blind Method; prucalopride; bisacodyl; high-resolution manometry; PEG; colon motility