Human symptoms–disease network

• Published in: Nature communications Vol. 5; no. 1; p. 4212
• Main Authors: Zhou, XueZhong, Menche, Jörg, Barabási, Albert-László, Sharma, Amitabh
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 26.06.2014; Nature Publishing Group
• Subjects: 631/92/360; 692/1807; 692/308; Bibliographic records; Cancer; Comorbidity; Disease; Disease - genetics; Genes; Genetic Predisposition to Disease; Genotype & phenotype; Humanities and Social Sciences; Humans; Medical research; Medical Subject Headings-MeSH; Models, Theoretical; multidisciplinary; Phenotype; Physics; Proteins - genetics; Science; Science (multidisciplinary); Systems Theory; Beijing China; Hungary; United States > US; China; Massachusetts

In the post-genomic era, the elucidation of the relationship between the molecular origins of diseases and their resulting phenotypes is a crucial task for medical research. Here, we use a large-scale biomedical literature database to construct a symptom-based human disease network and investigate t...