Cost-Effectiveness of Focal Mass Drug Administration and Mass Drug Administration with Dihydroartemisinin-Piperaquine for Malaria Prevention in Southern Province, Zambia: Results of a Community-Randomized Controlled Trial

• Published in: The American journal of tropical medicine and hygiene Vol. 103; no. 2_Suppl; pp. 46 - 53
• Main Authors: Yukich, Joshua O, Scott, Callie, Silumbe, Kafula, Larson, Bruce A, Bennett, Adam, Finn, Timothy P, Hamainza, Busiku, Conner, Ruben O, Porter, Travis R, Keating, Joseph, Steketee, Richard W, Eisele, Thomas P, Miller, John M
• Format: Journal Article
• Language: English
• Published: United States The American Society of Tropical Medicine and Hygiene 01.08.2020
• Subjects: Antimalarials - administration & dosage; Antimalarials - economics; Antimalarials - therapeutic use; Artemisinins - administration & dosage; Artemisinins - economics; Artemisinins - therapeutic use; Cost-Benefit Analysis; Disease Eradication - economics; Disease Eradication - methods; Drug Costs; Drug Therapy, Combination - economics; Drug Therapy, Combination - methods; Health Care Costs; Humans; Malaria, Falciparum - drug therapy; Malaria, Falciparum - economics; Malaria, Falciparum - epidemiology; Malaria, Falciparum - prevention & control; Mass Drug Administration - economics; Mass Drug Administration - methods; Plasmodium falciparum - drug effects; Quality-Adjusted Life Years; Quinolines - administration & dosage; Quinolines - economics; Quinolines - therapeutic use; Zambia - epidemiology; Zambia

Community-wide administration of antimalarial drugs in therapeutic doses is a potential tool to prevent malaria infection and reduce the malaria parasite reservoir. To measure the effectiveness and cost of using the antimalarial drug combination dihydroartemisinin-piperaquine (DHAp) through differen...