Age-associated changes in human CD4+ T cells point to mitochondrial dysfunction consequent to impaired autophagy - Bektas, Arsun; Schurman, Shepherd H.; Gonzalez-Freire, Marta; Dunn, Christopher A.; Singh, Amit K.; Macian, Fernando; Cuervo, Ana Maria; Sen, Ranjan; Ferrucci, Luigi (Aging (Albany, NY.), 2019)
Keywords: Adult; Aged; CD4-Positive T-Lymphocytes - metabolism; Cell Respiration; Humans; Immunosenescence; Longitudinal Studies; Mitochondria - metabolism; Mitochondria - ultrastructure; Mitophagy; Priority Research Paper; Young Adult; autophagy; CD4+ T cells; aging; proteomics; mitochondria