Systemic overexpression of C-C motif chemokine ligand 2 promotes metabolic dysregulation and premature death in mice with accelerated aging
Injection of tissues with senescent cells induces changes that mimic aging, and this process is delayed in mice engineered to eliminate senescent cells, which secrete proinflammatory cytokines, including C-C motif chemokine ligand 2 ( ). Circulating levels of correlate with age, but the impact of on...
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Published in | Aging (Albany, NY.) Vol. 12; no. 20; pp. 20001 - 20023 |
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Main Authors | , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
United States
Impact Journals
26.10.2020
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Subjects | |
Online Access | Get full text |
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