Clinical implications of using molecular diagnostics for ovarian cancers

• Published in: Annals of oncology Vol. 24 Suppl 10; no. Suppl 10; pp. x22 - x26
• Main Authors: Kohn, E C, Romano, S, Lee, J-M
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 01.12.2013
• Subjects: Biomarkers, Tumor - genetics; BRCA1 Protein - genetics; BRCA2 Protein - genetics; Female; Humans; Molecular Targeted Therapy; Mutation; Neoplasm Grading; Ovarian Neoplasms - diagnosis; Ovarian Neoplasms - genetics; Ovarian Neoplasms - pathology; Ovary - pathology; Pathology, Molecular; Prognosis; Symposium; morphological; therapeutics; molecular; biomarker; high-grade serous ovarian cancer

In the era of morphologic diagnostics, any epithelial tumor on or involving the ovaries was presumed to come from and be strictly of ovarian origin, apart from the rare but clearly metastatic tumors. Thus, many women who might have had small fallopian tube primary cancers that rapidly extended on to...