Mechanisms of inflammatory cell attachment in chronic relapsing experimental allergic encephalomyelitis: A scanning and high-voltage electron microscopic study of the injured mouse blood-brain barrier

• Published in: Microvascular research Vol. 41; no. 3; pp. 299 - 310
• Main Authors: Lossinsky, A.S., Pluta, R., Song, M.J., Badmajew, V., Moretz, R.C., Wisniewski, H.M.
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier Inc 01.05.1991; Elsevier
• Subjects: Animals; Biological and medical sciences; Blood-Brain Barrier; Brain - blood supply; Brain - ultrastructure; Cell Adhesion; Chronic Disease; Encephalomyelitis, Autoimmune, Experimental - pathology; Female; Lymphocytes - pathology; Lymphocytes - ultrastructure; Medical sciences; Mice; Microscopy, Electron, Scanning; Monocytes - pathology; Monocytes - ultrastructure; Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis; Neurology; Recurrence; Spinal Cord - blood supply; Spinal Cord - ultrastructure; Scanning electron microscopy; Animal model; Multiple sclerosis; Nervous system diseases; Encephalomyelitis; Rodentia; Autoimmune disease; Blood brain barrier; Inflammatory disease; Vertebrata; High voltage electron microscopy; Experimental disease; Mammalia; Mouse; Ultrastructure; Animal; Blood vessel

Brain and spinal cord blood vessels from mice subjected to chronic relapsing experimental allergic encephalomyelitis were examined by scanning (SEM) and high-voltage electron microscopy (HVEM). SEM analysis of veins and venules from affected tissue regions demonstrated inflammatory cells (ICs), prim...