Prolonged time course of population excitatory postsynaptic potentials in motoneurons of chronic stroke survivors

• Published in: Journal of neurophysiology Vol. 122; no. 1; pp. 176 - 183
• Main Authors: Son, Jongsang, Hu, Xiaogang, Suresh, Nina L., Rymer, William Z.
• Format: Journal Article
• Language: English
• Published: United States American Physiological Society 01.07.2019
• Series: Nervous System Pathophysiology
• Subjects: Adult; Aged; Excitatory Postsynaptic Potentials; Female; H-Reflex; Humans; Male; Middle Aged; Motor Neurons - physiology; Reaction Time; Stroke - physiopathology; double stimulation; spasticity; EPSP time course; reflex; stroke

Hyperexcitability of spinal motoneurons may contribute to muscular hypertonia after hemispheric stroke. The origins of this hyperexcitability are not clear, but we hypothesized that prolongation of the Ia excitatory postsynaptic potential (EPSP) in spastic motoneurons may be one potential mechanism,...