Intact encoding, impaired consolidation in procedural learning in Parkinson’s disease

• Published in: Experimental brain research Vol. 179; no. 4; pp. 703 - 708
• Main Authors: Cohen, Henri, Pourcher, Emmanuelle
• Format: Journal Article
• Language: English
• Published: Berlin Springer 01.06.2007; Springer Nature B.V
• Subjects: Anatomical correlates of behavior; Behavioral psychophysiology; Biological and medical sciences; Brain - metabolism; Brain - physiopathology; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases; Dopamine - deficiency; Female; Fundamental and applied biological sciences. Psychology; Humans; Language Tests; Learning; Learning Disabilities - etiology; Learning Disabilities - physiopathology; Learning Disabilities - psychology; Male; Medical sciences; Memory Disorders - etiology; Memory Disorders - physiopathology; Memory Disorders - psychology; Middle Aged; Neural Pathways - metabolism; Neural Pathways - physiopathology; Neurology; Neuropsychological Tests; Parkinson Disease - complications; Parkinson Disease - physiopathology; Parkinson Disease - psychology; Parkinson's disease; Psychology. Psychoanalysis. Psychiatry; Psychology. Psychophysiology; Human; Nervous system diseases; Parkinson's disease; Idiopathic; Parkinson disease; Mirror reading; Cerebral disorder; Learning; Acquisition process; Striatofrontal circuits; Central nervous system disease; Strategy; Degenerative disease; Procedural learning; Extrapyramidal syndrome

Idiopathic Parkinson's disease (IPD) patients and matched healthy participants were compared on a non-motor procedural task involving semantically related inverted word pairs, and 3 months later to determine the extent of skill consolidation. IPD patients were found to acquire new procedural sk...