Metabolic engineering of erythritol production from glycerol by Yarrowia lipolytica

• Published in: Biotechnology and bioprocess engineering Vol. 29; no. 1; pp. 119 - 127
• Main Authors: Wang, Ya-Ting, Zhao, Ling-Xuan, Wei, Liu-Jing, Chen, Jun, Liu, Zhijie, Liu, Feng, Hua, Qiang
• Format: Journal Article
• Language: English
• Published: Seoul The Korean Society for Biotechnology and Bioengineering 01.02.2024; Springer Nature B.V; 한국생물공학회
• Subjects: arabitol; Biotechnology; Byproducts; Chemistry; Chemistry and Materials Science; Dehydrogenase; Dehydrogenases; Erythritol; erythrose; Fructokinase; Glycerol; Industrial and Production Engineering; Mannitol; Mannitol 2-dehydrogenase; Metabolic engineering; Metabolism; Osmotic stress; Overexpression; oxidoreductases; Reductase; Reductases; Research Paper; Substrates; Synthesis; Transketolase; Yarrowia lipolytica; 생물공학; By-products; Metabolic engineering; Erythritol

Erythritol as a four-carbon polyol has been widely used in food, pharmaceutical and daily chemical industries with characteristics of low caloric value and high chemical stability. Here, a system metabolic engineering strategy was used to increase the yield of erythritol from glycerol in Yarrowia li...