Quantitative Fundus Autofluorescence in Healthy Eyes

• Published in: Investigative ophthalmology & visual science Vol. 54; no. 8; pp. 5684 - 5693
• Main Authors: Greenberg, Jonathan P., Duncker, Tobias, Woods, Russell L., Smith, R. Theodore, Sparrow, Janet R., Delori, François C.
• Format: Journal Article
• Language: English
• Published: United States The Association for Research in Vision and Ophthalmology 21.08.2013
• Subjects: Adolescent; Adult; Child; Child, Preschool; Continental Population Groups; Female; Fundus Oculi; Humans; Lipofuscin - metabolism; Male; Melanins - metabolism; Middle Aged; Ophthalmoscopes; Ophthalmoscopy - methods; Ophthalmoscopy - standards; Optical Imaging - instrumentation; Optical Imaging - methods; Optical Imaging - standards; Reference Values; Retina - cytology; Retina - metabolism; Retinal Pigment Epithelium - cytology; Retinal Pigment Epithelium - metabolism; Young Adult; lipofuscin; scanning laser ophthalmoscope; retinal pigment epithelium; retina; melanin; quantitative fundus autofluorescence

Fundus autofluorescence was quantified (qAF) in subjects with healthy retinae using a standardized approach. The objective was to establish normative data and identify factors that influence the accumulation of RPE lipofuscin and/or modulate the observed AF signal in fundus images. AF images were ac...