Kaptive 2.0: updated capsule and lipopolysaccharide locus typing for the Klebsiella pneumoniae species complex

• Published in: Microbial genomics Vol. 8; no. 3
• Main Authors: Lam, Margaret M. C., Wick, Ryan R., Judd, Louise M., Holt, Kathryn E., Wyres, Kelly L.
• Format: Journal Article
• Language: English
• Published: England Microbiology Society 01.03.2022
• Subjects: Genomics; Humans; Klebsiella; Klebsiella Infections - epidemiology; Klebsiella pneumoniae - genetics; Lipopolysaccharides; O locus; Klebsiella capsule K-locus genomic surveillance; K locus; Klebsiella pneumoniae

The outer polysaccharide capsule and lipopolysaccharide (LPS) antigens are key targets for novel control strategies targeting Klebsiella pneumoniae and related taxa from the K. pneumoniae species complex (KpSC), including vaccines, phage and monoclonal antibody therapies. Given the importance and gr...