Kinetics of T lymphocyte responses to persistent antigens

• Published in: Experimental and molecular pathology Vol. 80; no. 1; pp. 26 - 37
• Main Authors: Shanklin, Douglas R., Smalley, David L.
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier Inc 01.02.2006; Elsevier
• Subjects: Antigens - immunology; Biological and medical sciences; Breast Implants; Clonal expansion; Clonal regression; Cytokines - biosynthesis; Cytokines - immunology; Data normalization; Female; Humans; Immunologic Memory; Interleukin-2 - biosynthesis; Interleukin-2 - immunology; Investigative techniques, diagnostic techniques (general aspects); Kinetics of immune cell reaction; Mathematical methods in biology; Mathematics; Medical sciences; Models, Immunological; Pareto optimization; Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques; Silicone Gels; T cells; T-Lymphocytes - immunology; Time Factors; Kinetics of immune cell reaction; Pareto optimization; Mathematical methods in biology; T cells; Clonal expansion; Clonal regression; Data normalization; Regression; Biology; Mathematical method; Optimization; Anatomic pathology; T-Lymphocyte; Kinetics; T antigen; Cell

Long term sequential study of immune responses in the same individuals is difficult from the time commitment required and the problem of maintaining enough subjects to provide for comparative analysis. We closely studied one hundred women with silicone mammary devices through cross sectional analysi...