Identification of Acinetobacter baumannii loci for capsular polysaccharide (KL) and lipooligosaccharide outer core (OCL) synthesis in genome assemblies using curated reference databases compatible with Kaptive

• Published in: Microbial genomics Vol. 6; no. 3
• Main Authors: Wyres, Kelly L., Cahill, Sarah M., Holt, Kathryn E., Hall, Ruth M., Kenyon, Johanna J.
• Format: Journal Article
• Language: English
• Published: England Microbiology Society 01.03.2020
• Subjects: Acinetobacter baumannii - genetics; Bacterial Capsules - genetics; BioResource; Computer Simulation; Databases, Genetic; Genetic Loci; Genome, Bacterial; Polysaccharides, Bacterial - genetics; outer-core oligosaccharide; Acinetobacter baumannii; capsular polysaccharide; Kaptive; K locus; OC locus

Multiply antibiotic-resistant Acinetobacter baumannii infections are a global public health concern and accurate tracking of the spread of specific lineages is needed. Variation in the composition and structure of capsular polysaccharide (CPS), a critical determinant of virulence and phage susceptib...