Age-related immune-modulating properties of seminal fluid that control the severity of asthma are gender specific

• Published in: Aging (Albany, NY.) Vol. 11; no. 2; pp. 707 - 723
• Main Authors: Niikura, Yuichi, Ishii, Takashi, Murakami, Jurika, Narita, Tomoya, Fujita, Yoko, Negishi, Hiroaki, Taketani, Yuji, Yamashita, Naomi
• Format: Journal Article
• Language: English
• Published: United States Impact Journals 24.01.2019
• Subjects: Adult; Aging - physiology; Animals; Asthma - immunology; Bone Marrow Cells; Bronchoalveolar Lavage Fluid; Dendritic Cells; Female; Humans; Immunoglobulin E - blood; Interleukin-13 - blood; Male; Mice; Middle Aged; Ovalbumin - toxicity; Research Paper; Semen - immunology; Sex Characteristics; seminal fluid; asthma; aging; gender difference

Reproductive organs play a pivotal role in asthma development and progression, especially in women. Endocrine environment changes associated with the menstrual cycle, pregnancy, and menopause can exacerbate the clinical features of asthma. Factors secreted by reproductive organs may be responsible f...