Occupational exposure to diesel engine exhaust and alterations in immune/inflammatory markers: a cross-sectional molecular epidemiology study in China

• Published in: Carcinogenesis (New York) Vol. 38; no. 11; pp. 1104 - 1111
• Main Authors: Bassig, Bryan A, Dai, Yufei, Vermeulen, Roel, Ren, Dianzhi, Hu, Wei, Duan, Huawei, Niu, Yong, Xu, Jun, Shiels, Meredith S, Kemp, Troy J, Pinto, Ligia A, Fu, Wei, Meliefste, Kees, Zhou, Baosen, Yang, Jufang, Ye, Meng, Jia, Xiaowei, Meng, Tao, Wong, Jason YY, Bin, Ping, Hosgood, H Dean, Hildesheim, Allan, Silverman, Debra T, Rothman, Nathaniel, Zheng, Yuxin, Lan, Qing
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 26.10.2017
• Subjects: Adult; Air Pollutants, Occupational - adverse effects; Biomarkers - metabolism; Cancer Biomarkers and Molecular Epidemiology; Carcinogens; Case-Control Studies; China; Cross-Sectional Studies; Gasoline - adverse effects; Humans; Inflammation - chemically induced; Inflammation - metabolism; Lung - metabolism; Lung Neoplasms - etiology; Lung Neoplasms - metabolism; Male; Molecular Epidemiology - methods; Occupational Exposure - adverse effects; Prospective Studies; Risk Assessment; Vehicle Emissions

The relationship between diesel engine exhaust (DEE), a known lung carcinogen, and immune/inflammatory markers that have been prospectively associated with lung cancer risk is not well understood. To provide insight into these associations, we conducted a cross-sectional molecular epidemiology study...