Vitamin D metabolism and regulation in pediatric MSCs - Ruggiero, B.; Padwa, B.L.; Christoph, K.M.; Zhou, S.; Glowacki, J. (The Journal of steroid biochemistry and molecular biology, 2016)
Keywords: 17β-Estradiol; 1α-Hydroxylase; 25-Hydroxyvitamin D3 1-alpha-Hydroxylase - genetics; 25-Hydroxyvitamin D3 1-alpha-Hydroxylase - metabolism; Adults; Autocrine signalling; Bone marrow; Bone Marrow Cells - cytology; Bone Marrow Cells - drug effects; Bone Marrow Cells - metabolism; Bone turnover; Calcifediol - metabolism; Calcifediol - pharmacology; Cell Differentiation - drug effects; Child; Children; Cholestanetriol 26-Monooxygenase - genetics; Cholestanetriol 26-Monooxygenase - metabolism; Cytochrome P450 Family 2 - genetics; Cytochrome P450 Family 2 - metabolism; Enzyme-linked immunosorbent assay; Estrogen Receptor alpha - genetics; Estrogen Receptor alpha - metabolism; Estrogen receptors; Extra-renal; Female; Gene expression; Gene Expression Regulation - drug effects; Homeostasis; Humans; Hydroxylase; Hydroxylation; Low Density Lipoprotein Receptor-Related Protein-2 - genetics; Low Density Lipoprotein Receptor-Related Protein-2 - metabolism; Male; Marrow stromal cells; Mesenchymal Stem Cells - cytology; Mesenchymal Stem Cells - drug effects; Mesenchymal Stem Cells - metabolism; Metabolism; Osteoblastogenesis; Osteoblasts; Osteoblasts - cytology; Osteoblasts - drug effects; Osteoblasts - metabolism; Paracrine signalling; Polymerase chain reaction; Primary Cell Culture; Receptors, Calcitriol - genetics; Receptors, Calcitriol - metabolism; Sex differences; Sex Factors; Stromal cells; Vitamin D; Vitamin D receptors; Vitamin D3 24-Hydroxylase - genetics; Vitamin D3 24-Hydroxylase - metabolism; hMSC; PTH; VDR; Marrow stromal cells; 1α,25(OH)2D; ER; DBP; Vitamin D; 25(OH)D; CYP; Children; 1α-Hydroxylase; FGF23; BMI; Extra-renal