CNGB3 -Achromatopsia Clinical Trial With CNTF: Diminished Rod Pathway Responses With No Evidence of Improvement in Cone Function - Zein, Wadih M.; Jeffrey, Brett G.; Wiley, Henry E.; Turriff, Amy E.; Tumminia, Santa J.; Tao, Weng; Bush, Ronald A.; Marangoni, Dario; Wen, Rong; Wei, Lisa L.; Sieving, Paul A. (Investigative ophthalmology & visual science, 2014)
Keywords: Adult; Capsules; Ciliary Neurotrophic Factor - administration & dosage; Color Vision Defects - drug therapy; Color Vision Defects - metabolism; Color Vision Defects - physiopathology; Cyclic Nucleotide-Gated Cation Channels - metabolism; Dark Adaptation; Drug Implants; Electroretinography; Female; Follow-Up Studies; Humans; Male; Middle Aged; Prospective Studies; Retinal Rod Photoreceptor Cells - drug effects; Retinal Rod Photoreceptor Cells - physiology; Time Factors; Tomography, Optical Coherence; Young Adult; CNTF-releasing implant; human clinical trial; CNTF; cone photoreceptor; CNGB3; rod photoreceptor; achromatopsia; ECT implant