Epithelial Remodeling as Basis for Machine-Based Identification of Keratoconus

• Published in: Investigative ophthalmology & visual science Vol. 55; no. 3; pp. 1580 - 1587
• Main Authors: Silverman, Ronald H., Urs, Raksha, RoyChoudhury, Arindam, Archer, Timothy J., Gobbe, Marine, Reinstein, Dan Z.
• Format: Journal Article
• Language: English
• Published: United States The Association for Research in Vision and Ophthalmology 13.03.2014
• Subjects: Corneal Topography - methods; Epithelium, Corneal - diagnostic imaging; Epithelium, Corneal - pathology; Humans; Keratoconus; Models, Theoretical; ROC Curve; Tomography, Optical Coherence - methods; Ultrasonography; high‐frequency ultrasound; keratoconus; pachymetry; corneal epithelium

To develop and evaluate automated computerized algorithms for differentiation of normal and keratoconus corneas based solely on epithelial and stromal thickness data. Maps of the corneal epithelial and stromal thickness were generated from Artemis-1 very high-frequency ultrasound arc-scans of 130 no...