Design, synthesis and immunological evaluation of monophosphoryl lipid A derivatives as adjuvants for a RBD-hFc based SARS-CoV-2 vaccine - Su, Shiwei; Chen, Liqing; Yang, Menglan; Liang, Dan; Ke, Bixia; Liu, Zhongqiu; Ke, Changwen; Liao, Guochao; Liu, Liang; Luo, Xiang (MedChemComm, 2023)
Keywords: Adjuvants; Biochemistry & Molecular Biology; Biological activity; Biological effects; Chemistry; Chemistry, Medicinal; COVID-19; E coli; Functional groups; Hydrofluorocarbons; Immune response; Immunological enhancement; Immunology; Immunotherapy; Life Sciences & Biomedicine; Lipid A; Lipids; Monophosphoryl lipid A; Pharmacology & Pharmacy; Science & Technology; Severe acute respiratory syndrome coronavirus 2; TLR4 protein; Toll-like receptors; Vaccines; ACTIVATION; ACID; PROTEIN; ANALOGS